RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research.
For research use only. We do not sell to patients.
- CAS No.: 2665669-32-7
- Formula: C21H16ClN3O2S2
- Molecular Weight:441.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
RIPK3-IN-2 (0.3-20 μM; 42 h) inhibits HT-29 cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 14 h) inhibits MEF cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 18 h) inhibits L929 cell growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HT-29 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:42 hours
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Result:Showed EC50 value of 0.085 μM.
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Cell Line:MEF cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:14 hours
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Result:Showed EC50 value of 0.24 μM.
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Cell Line:L929 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:18 hours
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Result:Showed EC50 value of 0.21 μM.
Chemical Information
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CAS No. 2665669-32-7
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Molecular Weight 441.95
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Formula C21H16ClN3O2S2
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SMILES
O=S1(C=C(C2CC2)C3=C1C=C4C(NC5=CC6=C(SC=N6)C=C5)=CC=NC4=C3)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RIPK3-IN-2 Related Classifications
HY-148052 Related Classifications
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