S,S-DACH-Pt-SO4
S,S-DACH-Pt-SO4 is a platinum based drug. S,S-DACH-Pt-SO4 can cause cellular DNA damage. S,S-DACH-Pt-SO4 is toxic to sensitive cells but shows varying degrees of resistance to drug-resistant cells. S,S-DACH-Pt-SO4 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 66900-71-8
- Formula: C6H14N2O4PtS
- Molecular Weight:405.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 66900-71-8
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Molecular Weight 405.34
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Formula C6H14N2O4PtS
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SMILES
O=S1([O-][Pt+2]2([O-]1)[NH2][C@]3([H])[C@@](CCCC3)([H])[NH2]2)=O
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Synonyms
S,S-DACH-sulph
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)