S49076 hydrochloride
Based on 1 publication(s) in Google Scholar
S49076 hydrochloride is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1265966-31-1
- 分子式: C22H23ClN4O4S
- 分子量:474.96
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 S49076 hydrochloride
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生物活性
製品説明
化学情報
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CAS 番号 1265966-31-1
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分子量 474.96
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分子式 C22H23ClN4O4S
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SMILES
O=C(N1CC2=CC3=C(NC(/C3=C\C4=CC(CN5CCOCC5)=CN4)=O)C=C2)SCC1=O.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy. [Abstract]2019 Apr 18;10(1):1812. PMID: 31000705
溶剤 & 溶解度
体外:
DMSO : ≥ 31 mg/mL (65.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
参考文献
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1054 mL | 10.5272 mL | 21.0544 mL | 52.6360 mL |
| 5 mM | 0.4211 mL | 2.1054 mL | 4.2109 mL | 10.5272 mL | |
| 10 mM | 0.2105 mL | 1.0527 mL | 2.1054 mL | 5.2636 mL | |
| 15 mM | 0.1404 mL | 0.7018 mL | 1.4036 mL | 3.5091 mL | |
| 20 mM | 0.1053 mL | 0.5264 mL | 1.0527 mL | 2.6318 mL | |
| 25 mM | 0.0842 mL | 0.4211 mL | 0.8422 mL | 2.1054 mL | |
| 30 mM | 0.0702 mL | 0.3509 mL | 0.7018 mL | 1.7545 mL | |
| 40 mM | 0.0526 mL | 0.2632 mL | 0.5264 mL | 1.3159 mL | |
| 50 mM | 0.0421 mL | 0.2105 mL | 0.4211 mL | 1.0527 mL | |
| 60 mM | 0.0351 mL | 0.1755 mL | 0.3509 mL | 0.8773 mL |
S49076 hydrochloride 関連分類
HY-12965A 関連分類
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