Sanggenon O
Based on 1 Customer Validation
Sanggenon O is a mushroom tyrosinase inhibitor that can be isolated from Morus nigra, with an IC50 value of 1.15 μM.
For research use only. We do not sell to patients.
- Purity: 96.83%
- CAS No.: 101664-32-8
- Formula: C40H36O12
- Molecular Weight:708.71
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Calu-3 | CC50 |
24.9 μM
Compound: 13
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Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability
Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability
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[PMID: 36651644] |
| Hep 3B2 | IC50 |
1.03 μM
Compound: 7
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Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysis
Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysis
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[PMID: 19072214] |
| Hep 3B2 | IC50 |
2.08 μM
Compound: 7
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Inhibition of hypoxia-induced VEGF protein secretion in human Hep3B cells after 16 hrs by ELISA
Inhibition of hypoxia-induced VEGF protein secretion in human Hep3B cells after 16 hrs by ELISA
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[PMID: 19072214] |
| Hep 3B2 | IC50 |
8.75 μM
Compound: 7
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Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assay
Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assay
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[PMID: 19072214] |
| HSC-2 | CC50 |
73 μM
Compound: sanggenon O
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Cytotoxicity against human HSC2 cells
Cytotoxicity against human HSC2 cells
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[PMID: 11429996] |
Chemical Information
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CAS No. 101664-32-8
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Appearance Solid
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Molecular Weight 708.71
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Formula C40H36O12
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Color Light yellow to yellow
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SMILES
C/C(C)=C\C[C@]12[C@](C(C3=C(O)C([C@@H]4[C@@H]([C@@H](C5=C(C=C(C=C5)O)O)CC(C)=C4)C(C6=C(C=C(C=C6)O)O)=O)=C(O)C=C3O1)=O)(OC7=CC(O)=CC=C72)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sanggenon O Related Classifications
HY-N12810 Related Classifications
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