Schizolaenone C
Schizolaenone C is a natural product that can be found in Schizolaena hystrix. Schizolaenone C exhibits anti-proliferative and anti-oxidative activities.
For research use only. We do not sell to patients.
- CAS No.: 928760-56-9
- Formula: C25H28O6
- Molecular Weight:424.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BJ | EC50 |
7.5 μM
Compound: 10
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Cytotoxicity against human BJ cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human BJ cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
| CCRF-CEM | EC50 |
12.3 μM
Compound: 10
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Cytotoxicity against human CEM cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human CEM cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
| HeLa | EC50 |
6.3 μM
Compound: 10
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Cytotoxicity against human HeLa cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human HeLa cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
| MCF7 | EC50 |
<10 μM
Compound: 10
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Cytotoxicity against human MCF7 cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human MCF7 cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
| RPMI-8226 | EC50 |
7.1 μM
Compound: 10
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Cytotoxicity against human RPMI8226 cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human RPMI8226 cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
| THP-1 | EC50 |
8.5 μM
Compound: 10
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Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method
Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method
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[PMID: 20192247] |
| U-266 | EC50 |
1.9 μM
Compound: 10
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Cytotoxicity against human U266 cells assessed as viable cells after 72 hrs by calcein AM assay
Cytotoxicity against human U266 cells assessed as viable cells after 72 hrs by calcein AM assay
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[PMID: 20192247] |
Chemical Information
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CAS No. 928760-56-9
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Molecular Weight 424.49
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Formula C25H28O6
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SMILES
C/C(C)=C\CC/C(C)=C/CC1=C(C=C2O[C@H](C3=CC(O)=CC(O)=C3)CC(C2=C1O)=O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Murphy BT, et, al. Cytotoxic compounds of Schizolaena hystrix from the Madagascar rainforest. Planta Med. 2006 Oct;72(13):1235-8. [Content Brief]
[2]. Zima A, et, al. Antiradical and cytoprotective activities of several C-geranyl-substituted flavanones from Paulownia tomentosa fruit. Molecules. 2010 Aug 31;15(9):6035-49. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Schizolaenone C Related Classifications
HY-N11136 Related Classifications
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