Timonacic
Based on 2 publication(s) in Google Scholar
Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 444-27-9
- Formula: C4H7NO2S
- Molecular Weight:133.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Timonacic
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Biological Activity
Timonacic can form a chelate with palladium(II) chloride in a buffered medium. Based on this, a spectrophotometric method has been developed to effectively determine its content. This method exhibits a good linear relationship, high precision, and accuracy, and is suitable for pharmaceutical quality control[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 444-27-9
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Appearance Solid
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Molecular Weight 133.17
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Formula C4H7NO2S
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Color White to off-white
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SMILES
O=C(C1NCSC1)O
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Synonyms
1,3-Thiazolidine-4-carboxylic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
H2O : 14.29 mg/mL (107.31 mM; ultrasonic and warming and heat to 60°C)
DMSO : 6 mg/mL (45.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Bakry RS, et al. Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications. J Pharm Biomed Anal. 1998 May;17(1):95-101. [Content Brief]
[2]. H U Weber, et al. Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine. Arch Gerontol Geriatr. 1982 Dec;1(4):299-310. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 7.5092 mL | 37.5460 mL | 75.0920 mL | 187.7300 mL |
| 5 mM | 1.5018 mL | 7.5092 mL | 15.0184 mL | 37.5460 mL | |
| 10 mM | 0.7509 mL | 3.7546 mL | 7.5092 mL | 18.7730 mL | |
| 15 mM | 0.5006 mL | 2.5031 mL | 5.0061 mL | 12.5153 mL | |
| 20 mM | 0.3755 mL | 1.8773 mL | 3.7546 mL | 9.3865 mL | |
| 25 mM | 0.3004 mL | 1.5018 mL | 3.0037 mL | 7.5092 mL | |
| 30 mM | 0.2503 mL | 1.2515 mL | 2.5031 mL | 6.2577 mL | |
| 40 mM | 0.1877 mL | 0.9386 mL | 1.8773 mL | 4.6932 mL | |
| H2O | 50 mM | 0.1502 mL | 0.7509 mL | 1.5018 mL | 3.7546 mL |
| 60 mM | 0.1252 mL | 0.6258 mL | 1.2515 mL | 3.1288 mL | |
| 80 mM | 0.0939 mL | 0.4693 mL | 0.9386 mL | 2.3466 mL | |
| 100 mM | 0.0751 mL | 0.3755 mL | 0.7509 mL | 1.8773 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Timonacic Related Classifications
HY-B1169 Related Classifications
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