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TSQ

8 Cited Publications
Customer Review

Based on 8 publication(s) in Google Scholar

TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins. TSQ is a bidentate ligand, utilizing quinoline and sulfonamide nitrogens to coordinate Zn2+; it binds to Zn22+ in a 2:1 ligand to metal ratio (Ex/Em = 334/495 nm).

For research use only. We do not sell to patients.

  • Purity : 99.50%
  • CAS No.: 109628-27-5
  • Formula: C17H16N2O3S
  • Molecular Weight:328.39
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • TSQ Chemical Structure
    TSQ Chemical Structure
  • Experimental Validation Results for TSQ
  • Experimental Validation Results for TSQ
  • Experimental Validation Results for TSQ
  • Experimental Validation Results for TSQ
CAS No.: 109628-27-5
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Cell Imaging/Staining
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  • TSQ Chemical Structure
    TSQ Chemical Structure
    1/16
  • 1/16

    TSQ purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jun 16;23(1):447. [Abstract]

    Customer Validation
     Intracellular Zn2+ ions detection by TSQ (0.1 M; 30 min). The results showed that the intracellular Zn2+ ion content in the nanoparticle groups was significantly higher than that in the control group, with the siRNAPD−L1@HA-ZIF-8 group exhibiting the highest intracellular Zn2+ ion content.

  • 1/16

    TSQ purchased from MedChemExpress. Usage Cited in: J Control Release. 2025 Jun 10:382:113754. [Abstract]

    Customer Validation
     Intracellular Zn2+ release over time detected using TSQ (HaCaT cells, 30 μM, 30 min at 37 °C) zinc probes (white arrow: Zn2+ fluorescence signal).

  • 1/16

    TSQ purchased from MedChemExpress. Usage Cited in: Adv Healthc Mater. 2025 Sep;14(23):e2501009. [Abstract]

    Customer Validation
     TSQ intracellular Zn2+ probe detection of temporal changes in Zn2+ release from ZnO and H-ZnO in cells. White arrow indicates fluorescence signal of intracellular zinc ion release. To further clarify intracellular Zn2+ release, the TSQ (30 µM; 30 min) probe was used to detect fluorescence in L929 cells. After 15 min of ZnO treatment, intracellular Zn2+ levels significantly increased and continued to rise over time.

  • 1/16

    TSQ purchased from MedChemExpress. Usage Cited in: Acta Biomater. 2025 Apr 8:S1742-7061(25)00257-0. [Abstract]

    Customer Validation
     Representative images of TSQ (10 μM; 30 min), a fluorescent Zn2+ probe, in Caco-2 cells. The results showed that Zn and I3C combined treatment significantly increased blue fluorescence intensity.

  • TSQ