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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2193 Results for "
Growth factor
" in MedChemExpress (MCE) Product Catalog:
Products (2193)
2193 Results for "Growth factor" in MCE Product Catalog:
Cat. No.: HY-L075
3,061 compounds
Lung cancer is a major global health problem, as it is the leading cause of cancer-related deaths worldwide. Lung cancer is divided into two categories: small cell lung cancer and non-small cell lung cancer (NSCLC). Non-small cell lung cancer accounts for about 85 percent of lung cancers.
As with all cancers, lung cancer may be treated with surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy or a combination thereof. Targeted therapy is one of the most exciting developments in lung cancer medicine, especially for NSCLC. Extensive genomic characterization of NSCLC has led to the identification of molecular subtypes of NSCLC that are oncogene addicted and exquisitely sensitive to targeted therapies. These include activating mutations in epidermal growth factor receptor (EGFR) and BRAF or echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusions and ROS1 receptor tyrosine kinase fusions. These are important targets for target therapy.
MCE offers a unique collection of 3,061 compounds with identified and potential anti-lung cancer activity. These compounds target lung cancer’s major targets and signaling pathways. MCE anti-lung cancer compound library is a useful tool for anti-lung cancer drugs screening and other related research.
Cat. No.: HY-P702629
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLK2; EGF-Like Protein 9; Prev. EGFL9; DLK-2; Epidermal Growth factor-Like Protein 9; Delta-Like 2 Homolog (Drosophila); Protein Delta Homolog 2; Delta-Like 2 Homolog; EGF-Like-Domain, Multiple 9; Delta Like Non-Canonical Notch Ligand 2; MGC2487
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P80852A
Synonyms: SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming Growth factor-beta-signaling protein
Cat. No.: HY-L074
3,404 compounds
Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC).
Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer.
MCE supplies a unique collection of 3,404 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.
Cat. No.: HY-P705892
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706108
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P86830
Synonyms: 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; Insulin like Growth factor binding protein 10 antibody; Insulin-like Growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody;
Cat. No.: HY-P86957
Synonyms: CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; Methyl CpG binding protein splice variant 1 antibody; Methyl CpG binding protein splice variant 2 antibody; Methyl CpG binding protein splice variant 3 antibody; Methyl CpG binding protein splice variant 4 antibody; Methyl-CpG-binding domain protein 1 antibody; Methyl-CpG-binding protein MBD1 antibody; PCM 1 antibody; PCM1 antibody; Protein containing methyl-CpG-binding domain 1 antibody; Regulator of fibroblast Growth factor 2 (FGF 2) transcription antibody; RFT antibody; The regulator of fibroblast Growth factor 2(FGF 2) transcription antibody;
Cat. No.: HY-P702754
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FLT3; CD135 Antigen; Fms Related Receptor Tyrosine Kinase 3; FLK-2; CD135; Growth factor Receptor Tyrosine Kinase Type III; STK1; Receptor Protein-Tyrosine Kinase; FLK2; Fms-Related Tyrosine Kinase 3; Fms-Like Tyrosine Kinase 3; Fetal Liver Kinase 2; Receptor-Type Tyrosine-Protein Kinase FLT3; Fetal Liver Kinase-2; Fms Related Tyrosine Kinase 3; STK-1; Stem Cell Tyrosine Kinase 1; FLT-3; FL Cytokine Receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704615
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FLT3; CD135 Antigen; Fms Related Receptor Tyrosine Kinase 3; FLK-2; CD135; Growth factor Receptor Tyrosine Kinase Type III; STK1; Receptor Protein-Tyrosine Kinase; FLK2; Fms-Related Tyrosine Kinase 3; Fms-Like Tyrosine Kinase 3; Fetal Liver Kinase 2; Receptor-Type Tyrosine-Protein Kinase FLT3; Fetal Liver Kinase-2; Fms Related Tyrosine Kinase 3; STK-1; Stem Cell Tyrosine Kinase 1; FLT-3; FL Cytokine Receptor
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P86699
Synonyms: AQP 1; AQP-1; AQP1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; AQP CHIP; AQP1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.
Cat. No.: HY-P702521
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; Apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD91; LRP-1; LRP; DDH3; Prolow-Density Lipoprotein Receptor-Related Protein 1; KPA; Low Density Lipoprotein Receptor-Related Protein 1; LDL Receptor Related Protein 1; Transforming Growth factor-β Receptor Type V
Species:
Human
Source:
CHO
Cat. No.: HY-P705789
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MET; Soluble MET Variant 13; MET Proto-Oncogene, Receptor Tyrosine Kinase; Soluble MET Variant 14; Hepatocyte Growth factor Receptor; Soluble MET Variant 15; DFNB97; Soluble MET Variant 1; RCCP2; Soluble MET Variant 2; HGFR; Soluble MET Variant 3; Tyrosine-Protein Kinase Met; Soluble MET Variant 5; Scatter factor Receptor; Soluble MET Variant 6; Proto-Oncogene C-Met; Soluble MET Variant 7; HGF/SF Receptor; Soluble MET Variant 8; HGF Receptor; Soluble MET Variant 9; SF Receptor; Met Proto-Oncogene; Met Proto-Oncogene Variant I; MET Protein; Proto-Oncogenic Met Protein; AUTS9; Soluble MET Variant 10; C-Met; Soluble MET Variant 11; DA11; Soluble MET Variant 12
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P85604
Synonyms: ATP dependent RNA helicase DDX3X; ATP-dependent RNA helicase DDX3X; CAP Rf; DBX; DDX14; DDX3X; DDX3X_HUMAN; DEAD; Asp Glu Ala Asp; box polypeptide 3 X linked; DEAD box; DEAD box protein 3; DEAD box protein 3 X-chromosomal; DEAD box X isoform; DEAD/H; Asp Glu Ala Asp/His; box polypeptide 3; DEAD/H box 3; DEAD/H box 3, X-linked; Fibroblast Growth factor Inducible 14; Fin14; Helicase like protein 2; Helicase-like protein 2; HLP2; X isoform; X-chromosomal.
Cat. No.: HY-P70857
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth factor Receptor 3; C-ErbB3; Receptor Tyrosine-Protein Kinase ErbB-3; ErbB3-S; Proto-Oncogene-Like Protein C-ErbB-3; ErbB-3; C-ErbB-3; FERLK; CDNA FLJ43038 Fis, Clone BRTHA3002955, Highly Similar To Receptor Tyrosine-Protein Kinase ErbB-3; VSCN1; Lethal Congenital Contracture Syndrome 2; Erb-B2 Receptor Tyrosine Kinase 3; P180-ErbB3
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P74894
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth factor Receptor 3; C-ErbB3; Receptor Tyrosine-Protein Kinase ErbB-3; ErbB3-S; Proto-Oncogene-Like Protein C-ErbB-3; ErbB-3; C-ErbB-3; FERLK; CDNA FLJ43038 Fis, Clone BRTHA3002955, Highly Similar To Receptor Tyrosine-Protein Kinase ErbB-3; VSCN1; Lethal Congenital Contracture Syndrome 2; Erb-B2 Receptor Tyrosine Kinase 3; P180-ErbB3
Species:
Human
Source:
HEK293
Cat. No.: HY-P706044
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ERBB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180erbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 4; V-Erb-A Erythroblastic Leukemia Viral Oncogene Homolog 4; Tyrosine Kinase-Type Cell Surface Receptor HER4; Receptor Protein-Tyrosine Kinase; Human Epidermal Growth factor Receptor 4; Uncharacterized Protein ERBB4; Receptor Tyrosine-Protein Kinase ErbB-4; Alternative Protein ERBB4
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P85601
Synonyms: ATP dependent helicase SMARCA4; ATP-dependent helicase SMARCA4; BAF 190; BAF190; BAF190A; Brahma protein homolog 1; Brahma protein like 1; BRG1; BRG1 associated factor 190A; BRG1 protein; BRG1-associated factor 190A; BRM/SWI2 related gene 1; Global transcription activator homologous sequence; global transcription activator snf2l4; Homeotic gene regulator; hSNF2b; Mitotic Growth and transcription activator; MRD16; Nuclear protein GRB1; Protein brahma homolog 1; Protein BRG-1; Protein BRG1; RTPS2; SMARC A4; SMARCA4; SMCA4_HUMAN; SNF2; SNF2 beta; SNF2 like 4; SNF2-beta; SNF2B; SNF2L4; SNF2LB; Sucrose nonfermenting like 4; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; Transcription activator BRG1.
Cat. No.: HY-P85540
Synonyms: 2310012M03Rik; 3'-Tab1; MAP3K7IP 1; MAP3K7IP1; MGC57664; Mitogen activated protein kinase kinase kinase 7 interacting protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAB 1; TAB1; TAB1_HUMAN; TAK1 binding protein 1; TAK1-binding protein 1; TGF beta activated kinase 1 binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; Transforming Growth factor beta activated kinase binding protein 1.
Cat. No.: HY-P86719
Synonyms: Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185erbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
