Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2193 Results for "
Growth factor
" in MedChemExpress (MCE) Product Catalog:
Products (2193)
2193 Results for "Growth factor" in MCE Product Catalog:
23
23 Cited Publications
Synonyms: E-616452; SJN 2511
Target:
Research Areas:
RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes .
20
20 Cited Publications
Cat. No.: HY-P7110A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFA; Vascular Endothelial Growth factor A; VEGF; VPF; Vascular Permeability factor; Vascular Endothelial Growth factor A, Long Form; VEGF-A; L-VEGF; Vascular Endothelial Growth factor A121; Vascular Endothelial Growth factor A165; Vascular Endothelial G
Species:
Human
Source:
HEK293
20
20
Category:
Plants Other Families Extract Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Sunscreen Simple Phenylpropanols Phenols Cosmetic Research Phenylpropanoids Disease Research Fields Cancer
Target:
20
19
19
Target:
Research Areas:
19
Target:
Research Areas:
17
MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
16
16 Cited Publications
Synonyms: S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS
Salirasib is a Ras inhibitor that inhibits specifically both oncogenically activated Ras and growth factor receptor-mediated Ras activation, resulting in the inhibition of Ras-dependent tumor growth.
14
14 Cited Publications
Cat. No.: HY-P7066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic Fibroblast Growth factor; Fibroblast Growth factor 2 (Basic); Fibroblast Growth factor; Heparin-Binding Growth factor 2; Prostatropin; HBGF-2; FGF2A; FGF-2; FGF; Fibroblast Growth factor 2; Basic Fibroblast Growth factor BFGF
Species:
Mouse
Source:
E. coli
14
Target:
Research Areas:
NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity .
13
13 Cited Publications
Cat. No.: HY-P7278
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth factor Beta Polypeptide; PDGF2; Platelet-Derived Growth factor Subunit B; Platelet-Derived Growth factor, Beta Polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:
Rat
Source:
E. coli
13
13 Cited Publications
Cat. No.: HY-P7119
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB2; Transforming Growth factor, Beta 2; Transforming Growth factor Beta 2; BSC-1 Cell Growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor factor; TGF-Beta2; Transforming Growth factor Beta-2 Proprotein; Polyergin; Prepro-Transforming Growth factor
Species:
Human
Source:
HEK293
13
13 Cited Publications
Cat. No.: HY-P70653
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:
Mouse
Source:
HEK293
13
Target:
12
12 Cited Publications
Cat. No.: HY-P7070
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin Like Growth factor 1; IGF1A; IGF-I; MGF; Insulin-Like Growth factor 1; Insulin-Like Growth factor IB; Insulin-Like Growth factor I; Insulin-Like Growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-Like
Species:
Mouse
Source:
E. coli
12
12 Cited Publications
Cat. No.: HY-18314
CAS No.: 504433-23-2
Target:
Research Areas:
GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth .
12
12 Cited Publications
Cat. No.: HY-P7014
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF4; Heparin-Binding Growth factor 4; Prev. HSTF1; HSTF-1; HBGF-4; FGF-4; HST-1; Heparin Secretory-Transforming Protein 1; HST; Fibroblast Growth factor; Transforming Protein KS3; Oncogene HST; K-FGF; SRTD22; KFGF; KS3; Human Stomach Cancer, Transforming
Species:
Human
Source:
E. coli
12
12 Cited Publications
Synonyms: T-DXd (solution); DS-8201 (solution); DS-8201a (solution)
Target:
Research Areas:
Trastuzumab deruxtecan (T-DXd; DS-8201a) (solution) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
