1641 Results for "

2a

" in MedChemExpress (MCE) Product Catalog:
Products (1641)

1641 Results for "2a" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-P70517
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2a
Species:  
Mouse
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P80316
Synonyms: AML3, CBFA1, OSF2, PEBP2a, RUNX2, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, Polyomavirus enhancer-binding protein 2 alpha A subunit, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, CBF-alpha-1, OSF-2, PEA2-alpha A, PEBP2-alpha A

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC, IF-Tissue, mIHC

Reactivity:  

Human, Mouse, Rat

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6
6 Cited Publications
Cat. No.: HY-131615
CAS No.: 2804595-86-4
Purity:  99.79%
Target:  

Sodium Channel

Research Areas:  

Others

TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actions of PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na 2+ mobilisation from TPC2 than TPC-A1-N (HY-131614). TPC2-A1-P can be used to probe different functions of TPC2 channels in intact cells [2] .
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6
6 Cited Publications
Cat. No.: HY-P80920
Synonyms: TREM2; TREM-2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on myeloid cells 2

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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6
6 Cited Publications
Cat. No.: HY-P701242
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic Fibroblast Growth Factor; Fibroblast Growth Factor 2 (Basic); Fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2a; FGF-2; FGF; Fibroblast Growth Factor 2; Basic Fibroblast Growth Factor BFGF
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-124306
CAS No.: 496775-95-2
Purity:  99.75%
Synonyms: CID-888706
Target:  

Ras

Research Areas:  

Cancer

ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A .
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5
5 Cited Publications
Cat. No.: HY-151527
CAS No.: 2708177-73-3
Purity:  98.64%
Research Areas:  

Neurological Disease

PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD) .
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5
5 Cited Publications
Cat. No.: HY-P990679

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) [2].
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5
5 Cited Publications
Cat. No.: HY-P7091
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic Fibroblast Growth Factor; Fibroblast Growth Factor 2 (Basic); Fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2a; FGF-2; FGF; Fibroblast Growth Factor 2; Basic Fibroblast Growth Factor BFGF
Species:  
Rat
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-145232
CAS No.: 3016307-75-5
Purity:  98.76%
Synonyms: OGTAC-3
Research Areas:  

Neurological Disease Cancer

PhosTAC7 is a heterobifunctional molecule named as a Phosphorylation Targeting Chimera (PhosTAC). PhosTAC7 can dephosphorylate the PDCD4 protein, FOXO3a protein, and tau protein by recruiting serine/threonine protein phosphatase 2A (PP2A). PhosTAC7 offers the advantage of selectively modulating the phosphorylation state of individual target proteins, making it a promising tool for research in cancer and tau protein-related neurodegenerative diseases (Alzheimer's disease) [2].
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4
4 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway [2] .
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4
4 Cited Publications
Cat. No.: HY-N1957
CAS No.: 31271-07-5
Synonyms: γ-Mangostin
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer [2]. Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes [2] .
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4
4 Cited Publications
Cat. No.: HY-P80811
Synonyms: EIF2S1; EIF2a; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2a; eIF-2alpha

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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4
4 Cited Publications
Cat. No.: HY-P80725
Synonyms: NOS2; NOS2a; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Mouse, Rat

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4
4 Cited Publications
Cat. No.: HY-P7030
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2a
Species:  
Human
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P7030A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2a
Species:  
Human
Source:  
CHO
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4
4 Cited Publications
Cat. No.: HY-P7330
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic Fibroblast Growth Factor; Fibroblast Growth Factor 2 (Basic); Fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2a; FGF-2; FGF; Fibroblast Growth Factor 2; Basic Fibroblast Growth Factor BFGF
Species:  
Human
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-P74628
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G2a; Non-Pancreatic Secretory Phospholipase A2; Prev. PLA2B; Phospholipase A2; Prev. PLA2L; RASF-A; Phosphatidylcholine 2-Acylhydrolase 2a; PLA2S; Phospholipase A2, Membrane Associated; PLAS1; Group IIA Phospholipase A2; SPLA2; GIIC SPLA2; MOM1; Phosp
Species:  
Mouse
Source:  
P. pastoris
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3
3 Cited Publications
Cat. No.: HY-P80161
Synonyms: H2aFX, H2aX, Histone H2aX, H2a/x, Histone H2a.X

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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3
3 Cited Publications
Cat. No.: HY-112537B
CAS No.: 54010-71-8
Purity:  ≥98.0%
D-Glucose 6-phosphate sodium is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate sodium acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate sodium can be used in research related to non-insulin-dependent diabetes mellitus and heart failure [2].
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