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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
Factor X
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "Factor X" in MCE Product Catalog:
Cat. No.: HY-P9940
CAS No.: 1610943-06-0
Synonyms: ACE-910; RG6013
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Cat. No.: HY-E70544B
CAS No.: 9001-29-0
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Canine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Canine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Canine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Canine Factor X can be used in studies related to Factor X deficiency .
Cat. No.: HY-P990060
CAS No.: 2488745-86-2
Synonyms: Mim8
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Cat. No.: HY-E70110
CAS No.: 37288-54-3
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Endo-1,4-β-mannanase is an important catalyst that randomly cleaves the β-1,4-linkages in the main chain of mannan, releasing short-chain β-1,4-mannan and mannose. The catalytic activity of Endo-1,4-β-mannanase toward locust bean gum is enhanced by Mn 2+, Co 2+, Ca 2+, Ba 2+, Triton X-100, sodium azide and N-ethylmaleimide, completely inhibited by Hg 2+ and N-bromosuccinimide, and partially inhibited by EDTA and Cu 2+. Endo-1,4-β-mannanase can be used in studies related to plant hemicellulose degradation, biomass saccharification, elimination of anti-nutritional factors in feed, and manno-oligosaccharide prebiotics .
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SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a Kd value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing .
Cat. No.: HY-N6987
CAS No.: 29913-71-1
Cat. No.: HY-W107616
CAS No.: 7541-49-3
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Cat. No.: HY-130581
CAS No.: 86559-73-1
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Lipid X is a 2,3-diacylglucosamine-1-phosphate that serves as the monosaccharide precursor of lipid A, possessing both LPS antagonist and weak agonist activities. Lipid X exerts protective effects by inhibiting tumor necrosis factor production, monocyte procoagulant activity, and neutrophil priming. Lipid X may induce transient pulmonary hypertension, neutropenia, and mild pyrogenic effects in laboratory animals. Lipid X has low toxicity and no in vitro antibacterial activity, but it significantly reduces mortality following Gram-negative bacterial infection and endotoxin exposure. Lipid X tends to accumulate in liver tissue, binds to circulating cellular components, and can be converted to lipid Y through transesterification. Lipid X can be used in research on Gram-negative bacterial sepsis, endotoxemia, and associated pulmonary hypertension .
Synonyms: ATI-5923
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Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .
Cat. No.: HY-107966A
CAS No.: 37270-89-6
Synonyms: Nadroparin calcium (MW 3600-5000)
Cat. No.: HY-168328
CAS No.: 2238839-34-2
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FKK6 is a selective agonist for pregnane X receptor (PXR) with an EC50 of 1.2 µM. FKK6 exhibits good affinity with plasma proteins, and good metabolic metabolism in human microsomes. FKK6 inhibits PXR-related NF-κB signaling pathway, inhibits the expression of inflammatory factors, and exhibits anti-inflammatory activity against DSS (HY-116282)-induced colitis in mouse model .
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Cat. No.: HY-159986
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X-17 is a Vanin-1 Inhibitor with potent anti-inflammatory and antioxidant activities. X-17 repressrs the inflammatory factor expressions and myeloperoxidase activity, elevats the colonic glutathione reserve, and restors the intestinal barrier .
Cat. No.: HY-168712
CAS No.: 3053222-76-4
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FXIa-IN-15 (Compound (S)-10h) is an inhibitor for Factor XIa (FXIa) and plasma kallikrein (PKa) with an IC50 of 0.38 nM and 59.2 nM. FXIa-IN-15 exhibits anticoagulant efficacy, that extends 50% activated partial thromboplastin time (aPTT) with EC1.5X of 0.55 μM .
Cat. No.: HY-100652A
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O-Desmethyl apixaban sulfate sodium is the major circulating metabolite of Apixaban (HY-50667) in humans. O-Desmethyl apixaban sulfate sodium exhibits no inhibitory activity against human activated factor X (FXa), with a Ki > 20 μM .
Cat. No.: HY-107966
CAS No.: 37270-89-6
Synonyms: Nadroparin calcium (MW 15000-19000)
Cat. No.: HY-P991211
CAS No.: 2766038-73-5
Synonyms: STSP-0601
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Cat. No.: HY-121503
CAS No.: 68207-21-6
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FD44 is a phenothiazine small molecule that inhibits the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a, a key regulator of synapse number and neurotransmitter release probability. In the Drosophila genetic autism model of fragile X syndrome (FXS), FD44 restored normal synapse number and associative learning .
Cat. No.: HY-E70544A
CAS No.: 9001-29-0
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Bovine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Bovine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Bovine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Bovine Factor X can be used in studies related to Factor X deficiency .
Cat. No.: HY-P0001
CAS No.: 78310-77-7
Synonyms: TFX-Jelfa
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
