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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
HaCaT
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "HaCaT" in MCE Product Catalog:
2
2
Category:
other families Coumarins Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
2
Category:
1
1 Cited Publications
Cat. No.: HY-P3161
CAS No.: 936541-36-5
1
Category:
Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-171006
CAS No.: 701225-07-2
Target:
Research Areas:
IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury .
1
1
1 Cited Publications
Cat. No.: HY-171007
CAS No.: 708245-32-3
Research Areas:
IRF1-IN-2 (Compound I-19) is an IRF1 inhibitor. IRF1-IN-2 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-2 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1; inhibits the Pho of TKB1, upregulates GPX4 and downregulates FACL4). IRF1-IN-2 has a protective effect on ionizing radiation-induced inflammatory skin injury .
1
1 Cited Publications
Cat. No.: HY-19416
CAS No.: 286475-30-7
Target:
Research Areas:
AEOL-10150 pentachloride is a metalloporphyrin-catalyzed antioxidant and a superoxide dismutase mimetic. AEOL-10150 pentachloride scavenges ROS and RNS, and modulates the NF-κB signaling pathway. AEOL-10150 pentachloride has potent antioxidant and anti-inflammatory activities. AEOL-10150 pentachloride effectively mitigates tissue damage caused by radiation and chemical agents such as CEES (HY-W199190). AEOL-10150 pentachloride synergizes with radiotherapy to exert anticancer effects on prostate tumors .
1
1 Cited Publications
Cat. No.: HY-N6896
CAS No.: 40788-84-9
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Cancer
Target:
1
1
1
1 Cited Publications
Synonyms: Quercetin-3,3',4',7-tetramethylether
Cat. No.: HY-N1428S1
CAS No.: 287389-42-8
Cat. No.: HY-N1428S
CAS No.: 147664-83-3
Cat. No.: HY-N2228
CAS No.: 83104-87-4
Synonyms: (-)-EGCG-3''-O-ME
Category:
Flavonoids Flavanols Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae
Target:
Synonyms: CGA 279202
Research Areas:
Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .
Cat. No.: HY-N1428CA
CAS No.: 3522-50-7
Cat. No.: HY-W749694
CAS No.: 76735-58-5
Synonyms: Canniflavone
Category:
Synonyms: tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate
Target:
Research Areas:
Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
