1436 Results for "

MIC

" in MedChemExpress (MCE) Product Catalog:
Products (1436)

1436 Results for "MIC" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-17586A
CAS No.: 171500-79-1
Synonyms: MDL-63397; BI-397
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
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8
8 Cited Publications
Cat. No.: HY-B0974
CAS No.: 132-92-3
Synonyms: Meticillin sodium
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .
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8
8 Cited Publications
Cat. No.: HY-N0462
CAS No.: 23094-69-1
Synonyms: NP-004255
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .
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7
7 Cited Publications
Cat. No.: HY-17580
CAS No.: 873857-62-6
Synonyms: OPT-80; PAR-101
Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research .
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6
6 Cited Publications
Cat. No.: HY-W012875
CAS No.: 504-88-1
Synonyms: β-Nitropropionic acid; Bovinocidin
3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .
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6
6 Cited Publications
Cat. No.: HY-17647
CAS No.: 1620458-09-4
Synonyms: ETX0914; AZD0914
Research Areas:  

Infection

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.
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5
5 Cited Publications
Cat. No.: HY-N0941
CAS No.: 20931-37-7
Synonyms: β-Mangostin
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
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5
5 Cited Publications
Cat. No.: HY-B0319
CAS No.: 65899-73-2
Synonyms: UK-20349
Research Areas:  

Infection Cancer

Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy .
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4
4 Cited Publications
Cat. No.: HY-P1674A
CAS No.: 3053070-05-3
Synonyms: POL7080 TFA
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
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4
4 Cited Publications
Cat. No.: HY-13579
CAS No.: 1161233-85-7
Purity:  99.51%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
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4
4 Cited Publications
Cat. No.: HY-N2187
CAS No.: 43043-74-9
Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF. Deoxyshikonin inhibited colorectal cancer (CRC) through the PI3K/Akt/mTOR pathway. Deoxyshikonin has proangiogenesis effect and antitumor activity. Deoxyshikonin is an antibacterial agent against methicillin-resistant S. aureus (MRSA) and S. pneumonia (MIC=17 μg/mL) .
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4
4 Cited Publications
Cat. No.: HY-100725
CAS No.: 146204-42-4
Purity:  99.51%
Target:  

Bacterial

Research Areas:  

Infection

BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM .
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4
4 Cited Publications
Cat. No.: HY-12930
CAS No.: 1384984-18-2
Purity:  99.50%
Synonyms: VXc-486
Target:  

Topoisomerase Bacterial

Research Areas:  

Infection

SPR719 (VXc-486) is an orally active gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple agent-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively. SPR719 is promising for research of lung disease caused by non-tuberculous mycobacteria (NTM) .
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4
4 Cited Publications
Cat. No.: HY-P72701
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD9; CD9 Antigen (P24); Prev. MIC3; BA2; TSPAN29; Motility-Related Protein; MRP-1; BA-2/P24 Antigen; Tetraspanin-29; Antigen CD9; CD9 Antigen; Tetraspanin; P24; TSPAN-29; Cell Growth-Inhibiting Gene 2 Protein; Tspan-29; Motility Related Protein-1; DRAP-27
Species:  
Human
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-P70154
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPCAM; HEA125; Prev. TACSTD1; CO-17A; Prev. MIC18; EGP314; Prev. M4S1; EGP34; Tumor-Associated Calcium Signal Transducer 1; CD326; TROP1; MOC31; KSA; 17-1A; GA733-2; Ly74; Ber-Ep4; MH99; Ep-CAM; Membrane Component, Chromosome 4, Surface Marker (35kD Glyco
Species:  
Human
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-138301
CAS No.: 2494198-61-5
Purity:  99.48%
Synonyms: DS37262926
Target:  

Wnt β-catenin Apoptosis

Research Areas:  

Cancer

Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex .
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3
3 Cited Publications
Cat. No.: HY-P80610
Synonyms: CD9; MIC3; TSPAN29; GIG2; CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD antigen CD9

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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3
3 Cited Publications
Cat. No.: HY-P80610A
Synonyms: CD9; MIC3; TSPAN29; GIG2; CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD antigen CD9

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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3
3 Cited Publications
Cat. No.: HY-101479
CAS No.: 192314-93-5
Purity:  99.49%
Synonyms: AR-100
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
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3
3 Cited Publications
Cat. No.: HY-N0610
CAS No.: 140-10-3
Synonyms: Trans-3-Phenylacrylic acid
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 .
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