1. Cell Cycle/DNA Damage
    Anti-infection
  2. Topoisomerase
    Bacterial
  3. SPR719

SPR719 (Synonyms: VXc-486)

Cat. No.: HY-12930
Handling Instructions

SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively.

For research use only. We do not sell to patients.

SPR719 Chemical Structure

SPR719 Chemical Structure

CAS No. : 1384984-18-2

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Description

SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1].

IC50 & Target

gyrase B[1]

Molecular Weight

428.46

Formula

C₂₁H₂₅FN₆O₃

CAS No.

1384984-18-2

SMILES

O=C(NC1=NC2=CC(C3=CN=C(C(C)(O)C)N=C3)=C(F)C([[email protected]@H]4OCCC4)=C2N1)NCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SPR719VXc-486SPR 719SPR-719VXc486VXc 486TopoisomeraseBacterialInhibitorinhibitorinhibit

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