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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
beta-sheet
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "beta-sheet" in MCE Product Catalog:
Cat. No.: HY-P5917A
Synonyms: Vaejovis mexicanus peptide 24 TFA
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Cat. No.: HY-P4882
CAS No.: 183449-57-2
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Cat. No.: HY-P11309
CAS No.: 957365-81-0
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Cat. No.: HY-P4370
CAS No.: 342790-23-2
Cat. No.: HY-P10699
CAS No.: 487036-63-5
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Cat. No.: HY-P4873
CAS No.: 118068-30-7
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Cat. No.: HY-114884
CAS No.: 530112-00-6
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RS-0406 is a beta-sheet breaker targeting Amyloid-β. RS-0406 can inhibits Aβ(1-42) fibrillogenesis and protect against Aβ(1-42)-induced cytotoxicity in primary hippocampal neurons. RS-0406 can be used for the research of neurological disease, such as Alzheimer's disease (AD) .
Cat. No.: HY-P10155
CAS No.: 352653-12-4
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Cat. No.: HY-P5340
CAS No.: 339091-39-3
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Cat. No.: HY-P11231
CAS No.: 2780353-11-7
Synonyms: FUS(364-369)-TAT
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Cat. No.: HY-P5515
CAS No.: 409085-40-1
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Cat. No.: HY-P5967
CAS No.: 189064-06-0
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Cat. No.: HY-P10534
CAS No.: 873582-78-6
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ccβ is a 17-residue peptide that folds into a coiled-coil trimer at low temperatures and aggregates to form amyloid fibrils at high temperatures. ccβ serves as a simple model system for investigating α-helix to β-sheet conformational transitions and template-mediated aggregation processes associated with prion and amyloidogenic diseases. ccβ can be used in studies of prion diseases and Alzheimer's disease .
Cat. No.: HY-P5906
Synonyms: Citrullinated Aβ (1-40); Citrullinated Aβ40
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Cat. No.: HY-149509
CAS No.: 1510825-03-2
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α-Synuclein inhibitor 9 (Compound 20C) is an α-Synuclein inhibitor. α-Synuclein inhibitor 9 binds to cavities in mature α-synuclein fibrils and reduces the β-sheet structure. α-Synuclein inhibitor 9 inhibits A53T α-Syn aggregation. α-Synuclein inhibitor 9 has neuroprotective effect, improves brain functional connection and relieves motor dysfunction.α-Synuclein inhibitor 9 can be used for Parkinson’s disease (PD) research. .
Cat. No.: HY-13325
CAS No.: 71939-12-3
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Aβ aggregation modulator-1 is a stimulator of amyloid-β (Aβ) fibrillogenesis. Aβ aggregation modulator-1 binds hydrophobic residues in Aβ peptides and stabilizes β-sheet-rich protofibrils and fibrils. Aβ aggregation modulator-1 accelerates Aβ polymerization and reduces concentrations of small, toxic Aβ oligomers in heterogeneous aggregation reactions. Aβ aggregation modulator-1 suppresses long-term potentiation (LTP) inhibition by Aβ oligomers in hippocampal brain slices. Aβ aggregation modulator-1 can be used for the study of Alzheimer's disease (AD) .
Cat. No.: HY-P5917
CAS No.: 1373890-79-9
Synonyms: Vaejovis mexicanus peptide 24
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Cat. No.: HY-P1889A
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Bim BH3, Peptide IV TFA is an Aβ42-binding peptide and the pro-apoptotic BH3 domain of the BIM protein. Bim BH3, Peptide IV TFA binds Aβ42 with a Kd of 7.1 μM. Bim BH3, Peptide IV TFA modulates Aβ42 structure, fibrillization pathways, aggregate morphology, and membrane interactions, inhibiting fibril formation while enhancing protofibril assembly. Bim BH3, Peptide IV TFA promotes Aβ42 β-sheet formation and accelerates aggregation. Bim BH3, Peptide IV TFA enhances Aβ42 membrane internalization and bilayer stiffening. Bim BH3, Peptide IV TFA induces neuronal cell death by enhancing BH3-induced membrane interactions of Aβ42 prefibrillar species. Bim BH3, Peptide IV TFA can be used for research on Alzheimer's disease .
Cat. No.: HY-P12350
CAS No.: 1261043-80-4
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Ac-I3K-NH2 is a surfactant-like peptide. Ac-I3K-NH2 self-assembles into β-sheet nanofibers through β-sheet hydrogen bonding, hydrophobic interactions, and electrostatic repulsion. Ac-I3K-NH2 forms ribbon-like nanofibers with nanoscale widths, adopting a β-sheet conformation, with lateral stacking driven by isoleucine side-chain contacts. Ac-I3K-NH2 templates the sol-gel condensation of tetraethoxysilane, producing silica nanotubes. Ac-I3K-NH2 templates the synthesis of one-dimensional Pt nanostructures with P7A as a capping agent .
Cat. No.: HY-161658
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N-Caffeoyldopamine (Compound 6i) is an amyloid-beta aggregation inhibitor. N-Caffeoyldopamine can inhibit Aβ aggregation to form nano-rod-like structures, thereby preventing β-sheet formation. N-Caffeoyldopamine can be used for Alzheimer's disease research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
