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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
beta-sheet backbone
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "beta-sheet backbone" in MCE Product Catalog:
Cat. No.: HY-140654
Purity: ≥90.0%
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Biotin-PEG2000-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Biotin-PEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
Synonyms: 3-Phenylpropiophenone; β-Phenylpropiophenone
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Dihydrochalcone (3-Phenylpropiophenone) is a Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree .
Cat. No.: HY-P10578
CAS No.: 906357-94-6
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Cat. No.: HY-P2399
CAS No.: 957780-56-2
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Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide building block containing a pseudoproline, which is used in studies related to Fmoc solid-phase peptide synthesis. Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH inhibits premature β-sheet aggregation during solid-phase peptide synthesis .
Cat. No.: HY-W835959
CAS No.: 2361566-66-5
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ACI-3024 is an an orally active and highly selective Tau protein aggregation inhibitor. ACI-3024 decrease the β-sheet content and seeding properties of pathological Tau from different Tauopathies, leading to a significant rescue of the Tau-induced neurodegeneration and neuroinflammation in a cellular model. ACI-3024 is promising for research of neurodegenerative diseases .
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Aβ/tau aggregation-IN-1 is a potent Aβ1-42 β-sheets formation and tau aggregation inhibitor. The KD values of Aβ/tau aggregation-IN-1 with Aβ1-42 and tau are 160 μM and 337 μM, respectively. Aβ/tau aggregation-IN-1 can permeate the blood-brain barrier .
Cat. No.: HY-P10701
CAS No.: 581799-39-5
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Cat. No.: HY-P3688
CAS No.: 131438-74-9
Synonyms: Aβ (1-38); Aβ38
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Cat. No.: HY-N6730
CAS No.: 145040-09-1
Synonyms: Aminopentol
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Cat. No.: HY-135859
CAS No.: 2705545-44-2
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NH2-MPAA-NODA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone . NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.
Cat. No.: HY-135859A
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NH2-MPAA-NODA TFA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone . NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.
Cat. No.: HY-P6299
CAS No.: 944792-75-0
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Cat. No.: HY-P5917A
Synonyms: Vaejovis mexicanus peptide 24 TFA
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Cat. No.: HY-P11309
CAS No.: 957365-81-0
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Cat. No.: HY-P4370
CAS No.: 342790-23-2
Cat. No.: HY-W004283S2
CAS No.: 64118-45-2
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Cat. No.: HY-176960
CAS No.: 141895-16-1
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3-Amino-2-hydroxypropyl dihydrogen phosphate is a chemical modification complex of the DNA phosphate backbone, which can be used to study the interaction between HIV integrase (IN) and DNA .
Cat. No.: HY-156138A
CAS No.: 1260798-95-5
Cat. No.: HY-185060
CAS No.: 799854-49-2
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N-Acetyllactosamine-C2-NH2 (Compound β-D-Gal-(l-4)-β-D- GlcNAc-(l-4))-l-ethylamine) is a disaccharide compound and is the core backbone component for constructing sialylated glycans (sialosides) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
