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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
chalcones
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "chalcones" in MCE Product Catalog:
Synonyms: PS-IX; AM114
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Proteasome inhibitor IX (PS-IX; AM114) is a Chalcone derivative and a chymotrypsin-like activity of the 20S proteasome inhibitor with an IC50 value of ~1 μM. Proteasome inhibitor IX exhibits HCT116 p53 +/+ cells growth inhibitory activity with an IC50 value of 1.49 μM. Proteasome inhibitor IX has potent anticancer activity .
Synonyms: 4-Carbomethoxybenzaldehyde; 4-Carboxybenzaldehyde methyl ester; Terephthalaldehydic acid methyl ester; Methyl 4-formylbenzoate
Cat. No.: HY-N3007A
CAS No.: 25515-46-2
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Cat. No.: HY-W002179
CAS No.: 15164-44-0
Cat. No.: HY-N7591
CAS No.: 1393922-01-4
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Flavonoids Chalcones Leguminosae Millettia pachycarpa Benth. Plants Disease Research Fields Cancer
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Cat. No.: HY-N9551
CAS No.: 14917-41-0
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Flavonoids Chalcones Metabolic Disease Phenols Polyphenols Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Plants Umbelliferae Disease Research Fields
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Cat. No.: HY-N8786
CAS No.: 15097-74-2
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Flavonoids Chalcones Dracaena draco (L.) L. Agavaceae Plants
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Cat. No.: HY-N10917
CAS No.: 688360-06-7
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Cat. No.: HY-W023983
CAS No.: 611-91-6
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Chalcone dibromide is a useful synthon in the synthesis of a large number of bioactive molecules such as pyrazolines, hydroxy pyrazolines, isoxazoles etc. Chalcone dibromide possesses antioxidant effects against tumor cells by inhibiting superoxide production and lipid peroxidation. Chalcone dibromide can be used for cancer disease research .
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Flavonoids Chalcones Leguminosae Plants Brachypterum robustum (Roxburgh ex Candolle) Dalzell & Gibson
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Antioxidant agent-1 is a new chalcone derivative as a potential antioxidant agent.
Cat. No.: HY-W749844
CAS No.: 52218-19-6
Synonyms: 2',4,4',6'-Tetrahydroxy-3-methoxychalcone; 3-Methoxy-2',4',6',4-tetrahydroxychalcone
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Homoeriodictyol chalcone (2',4,4',6'-Tetrahydroxy-3-methoxychalcone; 3-Methoxy-2',4',6',4-tetrahydroxychalcone) is a non-selective antioxidant radical scavenger that neutralizes reactive oxygen species (ROS). Homoeriodictyol chalcone is promising for research of neurodegenerative diseases (e.g., Alzheimer’s), inflammatory disorders, and cancers .
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Anti-inflammatory agent 32 is a chalcone derivative with anti-inflammatory activity. Anti-inflammatory agent 32 can be used for the research of inflammatory bowel disease .
Cat. No.: HY-148568
CAS No.: 2883408-32-8
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TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor .
Cat. No.: HY-N8707
CAS No.: 34000-39-0
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other families Flavonoids Chalcones Monophenols Phenols Plants
Cat. No.: HY-N3007R
CAS No.: 73692-50-9
Chalcone 4 hydrate is an anti-parasitic agent. Chalcone 4 hydrate inhibits the growth and proliferation of Babesia and Theileria in vitro. Chalcone 4 hydrate reduces the viability of mammalian fibroblasts and kidney cells in vitro. Chalcone 4 hydrate can be used for the research of parasitic infections .
Cat. No.: HY-128452
CAS No.: 42220-77-9
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2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity .
Cat. No.: HY-145858
CAS No.: 2756846-09-8
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Chalcones A-N-5 is a trihydroxy chalcone derivative compound. Chalcones A-N-5 doesn’t show cytotoxicity at the concentration lower than 100 µM (with IC50 > 1 mM), but has a significant effect on promoting cell proliferation. Chalcones A-N-5 potentially promotes neuronal cell growth in the damaged brain tissue. Chalcones A-N-5 also inhibits ferroptosis induced by RSL or erastin and reduces the lipid peroxidation levels induced by Aβ1-42 protein aggregation. Chalcones A-N-5 is a promising molecular skeleton candidate for further development of lead compound for in vivo test to research AD .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
