147 Results for "

cross-linking agents.

" in MedChemExpress (MCE) Product Catalog:
Products (147)

147 Results for "cross-linking agents." in MCE Product Catalog:

Cat. No.: HY-112624M
CAS No.: 9004-54-0
Synonyms: Dextran 150; Dextran D150; Dextran T150(MW 130000-170000)
Dextran T150 (Dextran 150; Dextran D150) (MW 150,000) is a dehydrated glucose polymer with an average molecular weight of 150,000. Dextran T150 (MW 150,000) has excellent biodegradability and good biocompatibility, and can be used as a fluorescent labeling tracer and a high-molecular cross-linking agent .
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Cat. No.: HY-148424
CAS No.: 145325-57-1
Purity:  98.03%
Research Areas:  

Cancer

PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody–agent conjugates (ADCs), and it can be used for the research of cancer .
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Cat. No.: HY-B0245S
CAS No.: 116653-28-2
Busulfan-d8 is a deuterium labeled Busulfan. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
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Cat. No.: HY-B0245R
CAS No.: 55-98-1
Busulfan (Standard) is the analytical standard of Busulfan. This product is intended for research and analytical applications. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
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Cat. No.: HY-16405
CAS No.: 851627-62-8
Research Areas:  

Cancer

PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A .
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Cat. No.: HY-W092039
CAS No.: 1450754-38-7
Target:  

Drug Intermediate

Research Areas:  

Others

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine is a diazirine-containing crosslinking agent, and it is used in chemical probe synthesis .
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Cat. No.: HY-W006886
CAS No.: 945212-26-0
Research Areas:  

Others

Fmoc-(R)-2-(7-octenyl) Ala-OH is an unnatural Fmoc-protected amino acid and modification module. Fmoc-(R)-2-(7-octenyl) Ala-OH serves as a key building block for all-hydrocarbon cross-linking modification of antimicrobial peptides, and facilitates the generation of stapled peptide derivatives. When introduced into specific sites of the parent peptide, Fmoc-(R)-2-(7-octenyl) Ala-OH effectively increases the α-helix content of the peptide chain, thereby significantly enhancing its antimicrobial activity and proteolytic stability. Fmoc-(R)-2-(7-octenyl) Ala-OH is widely used in research on bacterial infections and the development of related antimicrobial agents . Stapled peptide is a specially chemically modified polypeptide. It locks the peptide chain into a stable α-helical structure by introducing a "staple"-like chemical bridge (usually an all-carbon backbone) at specific positions of the peptide chain.
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Cat. No.: HY-W013538
CAS No.: 5132-30-9
Synonyms: N,N'-Ethylenedimaleimide
Research Areas:  

Others

1,2-Bis(maleimido)ethane (N,N'-Ethylenedimaleimide) is a protein cross-linking agent.
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Cat. No.: HY-W075885
CAS No.: 14913-33-8
Synonyms: trans-platinumdiamminedichloride
trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) is a geometric isomer of Cisplatin (HY-17394). Trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage while exhibiting low cytotoxicity. Trans-Platinum(II)diammine dichloride is useful for studying DNA-protein cross-links .
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Cat. No.: HY-14572
CAS No.: 680199-06-8
Synonyms: SN 27858
Research Areas:  

Cancer

PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .
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Cat. No.: HY-159008
CAS No.: 2292112-27-5
Research Areas:  

Others

NHSF is a protein cross-linking agent .
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Cat. No.: HY-W763597
CAS No.: 56641-05-5
Poly(ethylene glycol) phenyl ether acrylate (MW 324) is a difunctional cross-linking agent .
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Cat. No.: HY-402091
CAS No.: 232931-64-5
Target:  

ADC Payloads

Research Areas:  

Others

SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA .
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Cat. No.: HY-W111005
CAS No.: 1086-00-6
Research Areas:  

Cancer

1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells .
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Cat. No.: HY-130545
CAS No.: 115616-51-8
Research Areas:  

Cancer

3-(Pyridin-2-yldisulfanyl)propanehydrazide is a crosslinking agent.
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Cat. No.: HY-W012887
CAS No.: 996-98-5
Oxalyldihydrazide is a crosslinking agent in proteomics research. Oxalyldihydrazide can capture carbonylated proteins on the surface of a microchip .
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Cat. No.: HY-Y0850U1
CAS No.: 9002-89-5
Synonyms: Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization)
PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) is a semicrystalline and biocompatible synthetic polymer with excellent safety properties including non-toxicity, no accumulation, and non-mutagenicity. PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) undergoes cross-linking via acetal bond formation between hydroxyl and aldehyde groups, and it can be used to prepare highly rigid, low-solubility degradable films as well as for dry or minimally invasive in vitro wound studies. PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) can construct a hydroxyl-rich microenvironment to trap photogenerated holes, thereby promoting hydrogen peroxide production and enhancing the redox cycle of iron species in the photo-Fenton reaction. PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) can act as a sacrificial agent and substrate to achieve synchronous degradation with pollutants, and it is applicable to sustainable waste management and water treatment .
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Cat. No.: HY-129630S
Purity:  99.19%
Tetrahydrocortisol-d5 is the deuterium labeled Tetrahydrocortisol. Tetrahydrocortisol is a metabolite of Hydrocortisone (HY-N0583) that fails to activate glucocorticoid receptor. Tetrahydrocortisol inhibits Dexamethasone (HY-14648)-induced formation of cross-linked actin networks. Tetrahydrocortisol acts as a synergist to enhance the activity of anticancer agents. Tetrahydrocortisol can be used in the research of primary open-angle glaucoma, ocular hypertension, lung cancer and breast cancer .
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Cat. No.: HY-W1048542
Fmoc-NH-PEG1000-COOH is a PEG product containing two Fmoc-protected amines and a carboxylic acid. Fmoc-NH-PEG1000-COOH is an important cross-linking agent with PEG chains .
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Cat. No.: HY-121713
CAS No.: 553-27-5
Purity:  99.36%
Synonyms: N,N-Bis(2-chloroethyl)aniline
Research Areas:  

Cancer

Aniline mustard (N,N-Bis(2-chloroethyl)aniline) is a DNA cross-linking agent. Aniline mustard can be released from quinone-based prodrugs after NQO1-mediated reduction. Aniline mustard exhibits antitumor activity in mice. Aniline mustard can be used for research on tumors .
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