112 Results for "

cyclic compounds

" in MedChemExpress (MCE) Product Catalog:
Products (112)

112 Results for "cyclic compounds" in MCE Product Catalog:

Cat. No.: HY-162459
CAS No.: 3036368-70-1
Research Areas:  

Inflammation/Immunology

cGAS-IN-3 (compound 30d-S) is an orally active cyclic GMP-AMP synthase (Cyclic GMP-AMP Synthase/cGAS) inhibitor with good plasma exposure and low clearance. cGAS-IN-3 has anti-inflammatory activity and can significantly reduce lung inflammation in rats .
loading...
    loading...
Cat. No.: HY-144329
CAS No.: 2259308-68-2
Target:  

STING

Research Areas:  

Inflammation/Immunology Cancer

STING agonist-11 (Compound 92) is a potent small molecule cyclic urea activator of STING with EC50 of 18 nM. Activation of STING is a highly promising approach in immunotherapy .
loading...
    loading...
Cat. No.: HY-161092
CAS No.: 1643463-59-5
Research Areas:  

Neurological Disease

KIO-301 chloride is an azobenzene photoswitch compound that can block voltage-gated ion channels, including hyperpolarisation-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium channels during exposure to visible light .
loading...
    loading...
Cat. No.: HY-161092A
Research Areas:  

Neurological Disease

KIO-301 chloride hydrochloride is an azobenzene photoswitchable compound that blocks voltage-gated ion channels, including hyperpolarization-activated cyclic nucleotide gating (HCN, during exposure to visible light) ) and voltage-gated potassium channels (voltage-gated potassium channels) .
loading...
    loading...
Cat. No.: HY-W040040A
CAS No.: 91464-90-3
γ-Cyclodextrin hydrate is an orally active cyclic oligosaccharide composed of eight glucose molecules, which can be formed by bacteria digesting starch. γ-Cyclodextrin hydrate can form water-soluble inclusion complexes with a variety of poorly soluble compounds and is widely used in fields such as pharmacy and food. In addition, γ-Cyclodextrin hydrate has good safety .
loading...
    loading...
Cat. No.: HY-W051391
CAS No.: 96556-05-7
Synonyms: Me3TACN
1,4,7-Trimethyl-1,4,7-triazonane, also known as TMT or trimethylenetris(aziridine), is a cyclic organic compound. TMT is commonly used as a crosslinking agent and a precursor for polymer and resin synthesis. In addition, it is used as a stabilizer in the production of polyurethane foam and as a curing agent for epoxy resins. Due to its high reactivity and stability, TMT is considered to be a versatile and efficient reagent in various applications.
loading...
    loading...
Cat. No.: HY-172271
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG1000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
loading...
    loading...
Cat. No.: HY-30156
CAS No.: 10592-27-5
Synonyms: 7-Azaindoline
Research Areas:  

Others

2,3-Dihydro-7-azaindole (7-Azaindoline) is a cyclic secondary amine substrate with a fused aromatic ring, which serves as a substrate for hydrogenation reactions. 2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of lipase from Pseudomonas stutzeri. 2,3-Dihydro-7-azaindole is often used as an intermediate in organic synthesis, for example, in the preparation of indole compounds .
loading...
    loading...
Cat. No.: HY-W074305
CAS No.: 108-97-4
Synonyms: γ-Pyrone
Target:  

Drug Derivative

Research Areas:  

Others

4H-pyran-4-one (γ-Pyrone) is a cyclic conjugated pyranone compound .
loading...
    loading...
Cat. No.: HY-156579
CAS No.: 2923009-48-5
Purity:  99.54%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-170362A
CAS No.: 2987886-48-4
Research Areas:  

Inflammation/Immunology

(R)-cGAS-IN-4 (Compound 77A*) is the R-enantiomer of cGAS-IN-4 (HY-170362). cGAS-IN-4 is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS) .
loading...
    loading...
Cat. No.: HY-W017512
CAS No.: 17496-14-9
Target:  

Drug Intermediate

Research Areas:  

Others

2-Methylindanone is a cyclic ketone compound. 2-Methylindanone is an important substrate for evaluating the effects of Pd and Ni in asymmetric α-arylation reactions. 2-Methylindanone can also be used as a drug intermediate .
loading...
    loading...
Cat. No.: HY-125357
CAS No.: 148619-41-4
Target:  

Inhibitory Antibodies

Research Areas:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
loading...
    loading...
Cat. No.: HY-156581
CAS No.: 2923009-95-2
Purity:  98.12%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

WRN inhibitor 5, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 5 can be used for the research of cancer, including cancers characterized by microsatellite instability (MSI) and/or defective DNA mismatch repair system (dMMR) .
loading...
    loading...
Cat. No.: HY-W016979
CAS No.: 705-86-2
δ-Decalactone is a hydrophobic natural cyclic lactone aroma compound with a creamy-coconut-peach aroma. It serves as a flavoring agent and a renewable monomer for ring-opening polymerization to prepare homopolymers and amphiphilic block copolymers, and it can self-assemble into degradable micelles for the encapsulation of hydrophobic molecules. δ-Decalactone is used in food flavoring and polymer materials research .
loading...
    loading...
Cat. No.: HY-N1074
CAS No.: 4449-55-2
Synonyms: Scandenolone
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50 of 3.5 μM.
loading...
    loading...
Cat. No.: HY-W016979R
CAS No.: 705-86-2
δ-Decalactone (Standard) is the analytical standard of δ-Decalactone (HY-W016979 ). This product is intended for research and analytical applications. δ-Decalactone is a hydrophobic natural cyclic lactone aroma compound with a creamy-coconut-peach aroma. It serves as a flavoring agent and a renewable monomer for ring-opening polymerization to prepare homopolymers and amphiphilic block copolymers, and it can self-assemble into degradable micelles for the encapsulation of hydrophobic molecules. δ-Decalactone is used in food flavoring and polymer materials research .
loading...
    loading...
Cat. No.: HY-W097929
CAS No.: 87-40-1
Synonyms: 2,4,6-Trichloroanisole
Tyrene (2,4,6-Trichloroanisole) is an off-flavor compound, cyclic nucleotide-gated (CNG) channel inhibitor, and olfactory transduction attenuator. Tyrene is formed by microbial O-methylation of 2,4,6-trichlorophenol. Tyrene inhibits channel activity in olfactory receptor cells by partitioning into the plasma membrane lipid bilayer, and also suppresses odorant- and cAMP-induced currents in individual olfactory receptor cells. Tyrene causes cork taint in wine. Tyrene also produces off-flavors in potato chips, dried fruits, coffee, and drinking water .
loading...
    loading...
Cat. No.: HY-177081
CAS No.: 2952542-22-0
Target:  

MEK

Research Areas:  

Cancer

Envometinib (Compound B) is a dual-MEK inhibitor that works through Deep Cyclic Inhibition (DCI). Envometinib has antitumor activity in various in vivo models. Envometinib can be studied in RAS and RAF mutated cancer such as colorectal cancer and melanoma .
loading...
    loading...
Cat. No.: HY-P11227
Research Areas:  

Neurological Disease

Compound 19A8.8 is a cyclic peptide derived from a CD36 protein fragment. Compound 19A8.8 inhibits the TGF-β/Smad3 signaling pathway by suppressing the interaction between TSP1 and CD36. Compound 19A8.8 has no obvious cytotoxicity. Compound 19A8.8 can be used for research on colon injury and fibrosis .
loading...
    loading...