43 Results for "

insulinotropic polypeptide

" in MedChemExpress (MCE) Product Catalog:
Products (43)

43 Results for "insulinotropic polypeptide" in MCE Product Catalog:

Cat. No.: HY-P3506CP
CAS No.: 2381089-83-2
Synonyms: LY3437943 (crude)
Target:  

GCGR GLP Receptor

Research Areas:  

Metabolic Disease

Retatrutide (LY3437943) (crude) is the crude form of Retatrutide (HY-P3506). Retatrutide is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity .
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Cat. No.: HY-P1731CP
CAS No.: 2023788-19-2
Tirzepatide (LY3298176) (crude) is the crude form of Tirzepatide (HY-P1731).Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
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Cat. No.: HY-P10881
CAS No.: 2758595-29-6
Research Areas:  

Metabolic Disease

Ganipatide is a 1-31-Glucose-dependent insulinotropic polypeptide. Ganipatide is promising for research of diabetes .
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Cat. No.: HY-P3577
CAS No.: 121765-67-1
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

[Tyr0] Gastric Inhibitory Peptide (23-42), human, a glucose-dependent insulinotropic polypeptide (GIP), is a weak inhibitor of gastric acid secretion that also stimulates insulin secretion. [Tyr0] Gastric Inhibitory Peptide (23-42), human can be used in diabetes, obesity research .
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Cat. No.: HY-P2080C
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

GIP (1-30)-Myr is the Myr-modified GIP (1-30), which is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) dose-dependently promotes insulin secretion over the range 10 -9-10 -6 M .
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Cat. No.: HY-10287A
CAS No.: 869490-47-1
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Gosogliptin hydrochloride is the hydrochloride of Gosogliptin (HY-10287). Gosogliptin (PF-00734200) is a potent, orally active, selective, and competitive inhibitor of DPP-IV, the enzyme mainly responsible for the degradation of the incretin peptides GLP-1 and glucose-dependent insulinotropic polypeptide. Gosogliptin demonstrates rapid and reversible inhibition of plasma DPP-4 activity. Gosogliptin stimulates insulin secretion and improves glucose tolerance .
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Cat. No.: HY-P0276F
Research Areas:  

Others

GIP, Cy5 labeled TFA is a Cy5-labeled gastric inhibitory polypeptide (GIP), which is specifically used to label endogenously/exogenously expressed glucose-dependent insulinotropic polypeptide receptor (GIPR) .
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Cat. No.: HY-P77949
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIP; Glucose-Dependent insulinotropic polypeptide; Gastric Inhibitory polypeptide; Incretin Hormone
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P74125A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GIP; Glucose-Dependent insulinotropic polypeptide; Gastric Inhibitory polypeptide; Incretin Hormone
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P702285
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Human
Source:  
E. coli Cell-free
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Cat. No.: HY-P702800
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P702801
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P702802
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P702803
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Cynomolgus
Source:  
P. pastoris
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Cat. No.: HY-P703990
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703685
Purity:  ≥ 95%, as determined by reducing Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P703965
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P703982
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide Receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide Receptor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-179332
CAS No.: 3059497-30-9
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GIPR antagonist 1 is a GIPR antagonist with an IC50 of 4.8 nM. GIPR antagonist 1 inhibits glucose-dependent insulinotropic polypeptide receptor signaling. GIPR antagonist 1 can be used for the research of type 2 diabetes and obesity .
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Cat. No.: HY-P12137
CAS No.: 2869056-74-4
Synonyms: RAY1225
Research Areas:  

Metabolic Disease

Bilpatide (RAY1225) is a dual agonist of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). Bilpatide is applicable to research related to obesity and diabetes .
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