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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
823 Results for "
B3
" in MedChemExpress (MCE) Product Catalog:
Products (823)
823 Results for "B3" in MCE Product Catalog:
3
Category:
Flavonoids Glycine max (L.) merr Flavones Other Diseases Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields
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3
3 Cited Publications
3
3 Cited Publications
2
2 Cited Publications
Synonyms: KDM4B Inhibitor B3
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NCGC00244536 is a potent KDM4B inhibitor with an IC50 of 10 nM.
2
2 Cited Publications
Cat. No.: HY-N0623S1
CAS No.: 115709-68-7
Synonyms: Tryptophan-13C; Tryptophane-13C
2
2 Cited Publications
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TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .
2
2 Cited Publications
Synonyms: Tryptophan (standard); Tryptophane (standard)
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2
2 Cited Publications
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Research Areas:
Nutlin-3b, the inactive form of Nutlin-3 (HY-50696), is a p53/MDM2 inhibitor with an IC50 of 13.6 μM. Nutlin-3b is 150 times less potent in binding to MDM2 than Nutlin-3a (HY-10029). Nutlin-3b is promising for research of cancers [3] .
2
2 Cited Publications
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(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models .
2
2 Cited Publications
Cat. No.: HY-P3252A
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2
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Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro [3] .
1
1 Cited Publications
Cat. No.: HY-N2345
CAS No.: 23567-23-9
1
1 Cited Publications
Cat. No.: HY-N0623S2
CAS No.: 202114-65-6
Synonyms: Tryptophan-13C11; Tryptophane-13C11
1
1 Cited Publications
Synonyms: Nicotinic acid (standard); Vitamin B3 (standard)
Category:
Alkaloids Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite
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1
1 Cited Publications
Cat. No.: HY-B0150S
CAS No.: 347841-88-7
Synonyms: Niacinamide-d4; Nicotinic acid amide-d4
1
1 Cited Publications
Cat. No.: HY-16561A
CAS No.: 61434-67-1
Target:
1
1 Cited Publications
Synonyms: Niacinamide(Standard); Nicotinic acid amide (Standard)
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Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity [3] .
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1
1 Cited Publications
Cat. No.: HY-RI00500
hsa-miR-27b-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
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1 Cited Publications
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GSK-3b Inhibitor XI (Compound 33) is a potent and selective GSK3β inhibitor, with a Ki value of 25 nM. GSK-3b Inhibitor XI increases glycogen synthase (GS) activity. GSK-3b Inhibitor XI can be used for research on type 2 diabetes and Alzheimer’s disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
