1. Epigenetics
  2. Histone Acetyltransferase
  3. Procyanidin B3

Procyanidin B3 

Cat. No.: HY-N2345 Purity: 99.63%
Handling Instructions

Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase).

For research use only. We do not sell to patients.

Procyanidin B3 Chemical Structure

Procyanidin B3 Chemical Structure

CAS No. : 23567-23-9

Size Price Stock Quantity
1 mg USD 229 In-stock
Estimated Time of Arrival: December 31
5 mg USD 686 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Procyanidin B3:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase)[1].

IC50 & Target

p300[1]

Molecular Weight

578.52

Formula

C30H26O12

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (86.43 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7285 mL 8.6427 mL 17.2855 mL
5 mM 0.3457 mL 1.7285 mL 3.4571 mL
10 mM 0.1729 mL 0.8643 mL 1.7285 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.32 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.32 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: 99.63%

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Product Name:
Procyanidin B3
Cat. No.:
HY-N2345
Quantity:
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