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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
237 Results for "
Ionizing
" in MedChemExpress (MCE) Product Catalog:
Products (237)
237 Results for "Ionizing" in MCE Product Catalog:
1
1 Cited Publications
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
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1 Cited Publications
5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
1
1 Cited Publications
Cat. No.: HY-145799A
Purity: 98.03%
5A2-SC8 TFA is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 TFA LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
1
1 Cited Publications
Cat. No.: HY-171006
CAS No.: 701225-07-2
Target:
Research Areas:
IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury .
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1 Cited Publications
Cat. No.: HY-171007
CAS No.: 708245-32-3
Research Areas:
IRF1-IN-2 (Compound I-19) is an IRF1 inhibitor. IRF1-IN-2 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-2 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1; inhibits the Pho of TKB1, upregulates GPX4 and downregulates FACL4). IRF1-IN-2 has a protective effect on ionizing radiation-induced inflammatory skin injury .
1
1 Cited Publications
Cat. No.: HY-W089645
CAS No.: 24589-78-4
Synonyms: N-Methyl-n-trimethylsilyltrifluoroacetamide
Target:
Research Areas:
2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product commonly used for silylation reactions in analyticalchemistry. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in the derivatization step of metabolomics analysis with gas chromatography/mass spectrometry (GC/MS) or as a derivatization reagent in GC with flame ionization detection analysis. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in research for studying Tamoxifen (HY-13757A) resistant breast cancer cells and other disease pathways .
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1 Cited Publications
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T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50=27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice.
Lipid 15 is an ionizable lipid with an ethanolamine linker and acid-sensitive hydrophobic tail. Lipid 15 can be used for the generation of Lipid nanoparticles (LNPs) and drug delivery research .
Cat. No.: HY-W755338
CAS No.: 20374-46-3
Synonyms: Cl-CCA
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4-Chloro-α-cyanocinnamic acid (Cl-CCA) is an advanced, rationally designed MALDI (Matrix-assisted laser desorption ionization) matrix .
Cat. No.: HY-160439
CAS No.: 2763904-72-7
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Ionizable lipid-2 is a cationic lipid for nucleic acid delivery, with the ability to form lipid nanoparticle mRNA vaccines that exhibit in vitro stability and immunostimulatory activity. Ionizable lipid-2 can be used in studies related to herpes zoster, mRNA vaccines and nucleic acid delivery .
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
Cat. No.: HY-W014815
CAS No.: 223463-14-7
Synonyms: 2-Bromopyridine-5-boronic acid
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Research Areas:
BPBA (2-Bromopyridine-5-boronic acid) is a derivatization reagent derived from Boric acid (HY-Y0314) with enhanced ionization efficiency in positive-mode electrospray ionization mass spectrometry. BPBA forms boronate ester derivatives with vicinal diols. It enables rapid, catalyst-free labeling operations, improves the detection sensitivity of liquid chromatography/mass spectrometry, and reduces false positive errors .
Cat. No.: HY-W598178
CAS No.: 2227214-78-8
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 is applicable for mRNA delivery .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
