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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
168 Results for "
Platelet activating factor
" in MedChemExpress (MCE) Product Catalog:
Products (168)
168 Results for "Platelet activating factor" in MCE Product Catalog:
Research Areas:
YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes.
Cat. No.: HY-105198
CAS No.: 139133-26-9
Synonyms: BB-882
Research Areas:
Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the research of acute pancreatitis.
Cat. No.: HY-N2892
CAS No.: 97399-91-2
Synonyms: Aristololactam A IIIa; Sch 546909
Category:
Annonaceae Extract Fissistigma balansae (A. DC.) Merr. Antibiotics Plants Disease Research Anticancer Other Antibiotics
Target:
Cat. No.: HY-108908A
CAS No.: 122957-06-6
Synonyms: UK-80067
Research Areas:
Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor (PAF) antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505 .
Cat. No.: HY-121007
CAS No.: 114776-28-2
Synonyms: Web2170
Research Areas:
Bepafant (Web2170) is a platelet-activating factor (PAF) antagonist that protects against anaphylactic lethality in active and passive anaphylaxis models in mice and guinea pigs in a dose-dependent manner and attenuates bronchoconstriction and blood pressure changes in anaphylaxis.
Cat. No.: HY-U00040
CAS No.: 115621-84-6
Research Areas:
PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.
Cat. No.: HY-101731
CAS No.: 167011-22-5
Target:
Research Areas:
CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively .
Cat. No.: HY-118019
CAS No.: 23758-16-9
Cat. No.: HY-N8218
CAS No.: 14982-11-7
Cat. No.: HY-177598
CAS No.: 123852-99-3
Research Areas:
F-0401 is a calcium antagonist with platelet-activating factor receptor (PAFR) antagonistic action. F-0401 can be used for the research of neurological disease, such as stroke .
Synonyms: SCH-37370
Research Areas:
N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC50 of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma .
Cat. No.: HY-106833
CAS No.: 115621-81-3
Research Areas:
SDZ-62-434 free base is a platelet-activating factor (PAF) antagonist. SDZ-62-434 free base has antiproliferative activity in human solid and haematological malignancies .
Cat. No.: HY-N11920
CAS No.: 145701-13-9
Cat. No.: HY-106899
CAS No.: 135947-75-0
Research Areas:
MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .
Cat. No.: HY-W040221
CAS No.: 85405-03-4
Research Areas:
Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor (PAF). Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold .
Cat. No.: HY-19097
CAS No.: 125030-71-9
Research Areas:
Ro 24-4736 is a potent, selective, p.o.-active platelet-activating factor (PAF) antagonist with a long duration of action. Ro-24-4736 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-101594
CAS No.: 116289-53-3
Synonyms: RP 59227
Research Areas:
Tulopafant is a platelet activating factor (PAF) antagonist.
Cat. No.: HY-101675
CAS No.: 132418-35-0
Synonyms: BN-50727
Research Areas:
Setipafant is a platelet-activating factor (PAF) antagonist.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
