82 Results for "

cavity

" in MedChemExpress (MCE) Product Catalog:
Products (82)

82 Results for "cavity" in MCE Product Catalog:

Cat. No.: HY-W001952
CAS No.: 15231-91-1
6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria .
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Cat. No.: HY-150137
CAS No.: 78649-41-9
Purity:  99.36%
Research Areas:  

Others

Iomeprol is a nonionic X-ray contrast agent with low osmotic pressure, stable chemical properties, and can withstand high temperature sterilization. Iomeprol can be widely used in vascular, body cavity, and gastrointestinal angiography examinations .
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Cat. No.: HY-114508
CAS No.: 1083-30-3
Purity:  99.87%
Synonyms: 3-Phenylpropiophenone; β-Phenylpropiophenone
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Dihydrochalcone (3-Phenylpropiophenone) is a Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree .
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Cat. No.: HY-N7434S
CAS No.: 1346603-41-5
Synonyms: Diethylnitrosamine-d4; DEN-d4; DENA-d4
N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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Cat. No.: HY-B0050
CAS No.: 79874-76-3
Target:  

Bacterial

Research Areas:  

Infection

Delmopinol is an antimicrobial agent that can be used in the oral cavity to inhibit the formation of dental biofilm.
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Cat. No.: HY-145937
CAS No.: 2413987-20-7
Purity:  98.50%
Target:  

MDM-2/p53

Research Areas:  

Cancer

PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations.
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Cat. No.: HY-116188
CAS No.: 1520083-61-7
Target:  

Others

Research Areas:  

Inflammation/Immunology

HX1 is a potent reversible myeloperoxidase (MPO) inhibitor with an IC50 value of 50 nM. HX1 is bound within the active site cavity above the heme and blocks the substrate channel. HX1 is promising for research of inflammatory diseases .
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Cat. No.: HY-107201A
CAS No.: 68168-23-0
Synonyms: Betadex hydrate
Research Areas:  

Others

β-Cyclodextrin hydrate (Betadex hydrate) is a cyclic oligosaccharide composed of seven glucose units, featuring a hydrophobic central cavity and a hydrophilic outer surface. β-Cyclodextrin hydrate is utilized in an immunoassay method that leverages the complex formed by β-Cyclodextrin hydrate with small molecules to enhance the sensitivity of the immunodetection for these small molecules. β-Cyclodextrin hydrate is applicable for research in biosensing and immunoanalysis .
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Cat. No.: HY-B0050A
CAS No.: 98092-92-3
Target:  

Bacterial

Research Areas:  

Infection

Delmopinol hydrochloride is an antimicrobial agent that can be used in the oral cavity to inhibit the formation of dental biofilm .
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Cat. No.: HY-W615797
CAS No.: 531-76-0
Target:  

Drug Derivative

Research Areas:  

Cancer

DL-Sarcolysine is an alkylating agent-based antitumor agent. DL-Sarcolysine shows significant inhibitory activity against solid tumors transplanted subcutaneously and in the abdominal cavity .
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Cat. No.: HY-P11446A
Research Areas:  

Cancer

AE105 TFA is a 9-mer peptide probe targeting the urokinase-type plasminogen activator receptor (uPAR). AE105 TFA binds tightly to the uPA-binding cavity of uPAR. AE105 TFA can be used for the study of cancer .
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Cat. No.: HY-106526
CAS No.: 13741-18-9
Synonyms: Bactacine; Nanbacine
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Xibornol (Bactacine) has strong antibacterial action against Streptococcus pneumoniae, Streptococcus pyogenes, and Staphyloccus aureus, as well as against Actinomyces israelii and Corynebacterium ulcerans. Xibornol has the potential for using for the antisepsis of the oral cavity and as adjuvant in pharyngeal infections caused by Gram-positive microorganisms .
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Cat. No.: HY-185048
PCB-OAA is a biocompatible multivinyl polycarboxybetaine macromonomer and that exhibits anti-fouling activity. PCB-OAA can form a hydrogel in vitreous cavity and shows an appealing ability to prevent significantly inflammatory response, fibrosis and complications such as raised intraocular pressure, and cataract formation. PCB-OAA can be used for the research of vitreous substitution .
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Cat. No.: HY-P11309
CAS No.: 957365-81-0
Research Areas:  

Neurological Disease

QL6 peptide is a self-assembling peptide. QL6 peptide can self-assembles into β-sheets bridging the cavity at neutral pH and improves the inhibitory environment by reducing inflammation and tissue scaring. QL6 peptide can be used for synthesis nanofiber scaffolds for spinal cord injuries (SCI) research .
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Cat. No.: HY-W012248
CAS No.: 349-58-6
Target:  

FGFR

Research Areas:  

Cancer

KG-655 is a ligand that specifically binds to the ARNT PAS-B domain. KG-655 binds to the internal cavity of ARNT PAS-B to restrict its variable folded conformation, disrupts the interaction between ARNT PAS-B and the transcriptional coactivator TACC3, and promotes the homodimerization of ARNT PAS-B. KG-655 is widely applicable to cancer-related research .
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Cat. No.: HY-N7434R
CAS No.: 55-18-5
Synonyms: Diethylnitrosamine (Standard); DEN (Standard); DENA (Standard)
N-Nitrosodiethylamine (Standard) is the analytical standard of N-Nitrosodiethylamine. This product is intended for research and analytical applications. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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Cat. No.: HY-121496
CAS No.: 642473-62-9
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. 3M-011 significantly inhibits H3N2 influenza viral replication in the nasal cavity. 3M-011 is also a potent adjuvant to radiotherapy that induces local and profound systemic immune responses during radiotherapy. 3M-011 strongly has antitumor action .
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Cat. No.: HY-B1390AR
CAS No.: 128-44-9
Research Areas:  

Infection

Saccharin (sodium) (Standard) is the analytical standard of Saccharin (sodium). This product is intended for research and analytical applications. Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .
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Cat. No.: HY-Y0788R
CAS No.: 496-15-1
Indoline (Standard) is an analytical standard for Indoline (HY-Y0788). This product is intended for research and analytical applications. Indoline is a HIV-1 envelope glycoprotein gp120 binder. Indoline binds to the conserved CD4-binding site of gp120 (the Phe 43 cavity and its surrounding vestibule), competitively blocks the binding of CD4, and prematurely triggers conformational changes of the Env trimer, resulting in viral inactivation. Indoline induces the conformational opening of HIV-1 Env on infected cells, exposes vulnerable epitopes, increases antibody recognition rate, enhances the binding of FcγRIIIa receptors, and sensitizes infected cells to antibody-dependent cellular cytotoxicity. Indoline is a derivative of Indole (HY-W001132). Indoline can be used in studies related to HIV-1 infection .
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Cat. No.: HY-10445
CAS No.: 219923-85-0
Synonyms: Azoline; R126638
Target:  

Fungal

Research Areas:  

Infection

Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
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