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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
485 Results for "
insect morphogenesis
" in MedChemExpress (MCE) Product Catalog:
Products (485)
485 Results for "insect morphogenesis" in MCE Product Catalog:
Cat. No.: HY-W587689
CAS No.: 120293-93-8
Synonyms: Juvenile hormone III bisepoxide; Juvenile hormone bisepoxide; JHB3
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Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research .
Cat. No.: HY-110381R
CAS No.: 1962931-71-0
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JNJ-DGAT2-A (Standard) is the analytical standard of JNJ-DGAT2-A (HY-110381). This product is intended for research and analytical applications. JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis .
Synonyms: NBAD hydrochloride
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Alkaloids Neurological Disease Other Alkaloids Phenols Polyphenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-180460
CAS No.: 339231-67-3
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SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM .
Cat. No.: HY-180500
CAS No.: 349561-46-2
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SCPI-3 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.159 µM; AeSCP-x IC50 = 0.285 µM). SCPI-3 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 3.09 µM in Aag-2 cells). SCPI-3 shows insecticidal activity against Aedes aegypti with a LD50 of 12.3 µM .
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o,p'-DDT (2,4'-DDT) is a chlorinated organic pesticide with estrogenic activity. o,p'-DDT is persistent in the environment, can accumulate in organisms and disrupt the endocrine system. o,p'-DDT is used in agriculture as a pesticide, especially for controlling insect pests. The use of o,p'-DDT has led to toxic effects in organisms, raising widespread concern about its environmental and health effects. o,p'-DDT has also led to research into its long-term effects in ecosystems .
Cat. No.: HY-E72096
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Human CYP2B6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2B6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2B6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a minor but highly polymorphic hepatic metabolic enzyme that metabolizes various prodrugs or xenobiotics .
Cat. No.: HY-E72099
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Human CYP2C19, Reductase+b5 is a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2C19, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2C19 is a human cytochrome P450 subtype belonging to the CYP2 family, as well as a major metabolic enzyme. It is predominantly expressed in the human liver and metabolizes various psychoactive compounds .
Cat. No.: HY-N13069
CAS No.: 86577-96-0
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Cat. No.: HY-W004303S
CAS No.: 1809273-36-6
Synonyms: Tetradecyl Aldehyde-d27
Cat. No.: HY-W017140S
CAS No.: 1335436-01-5
Synonyms: SBMP-d3
Cat. No.: HY-W130074
CAS No.: 1686-14-2
α-Pinene oxide is a type of monoterpene epoxidation intermediate. α-Pinene oxide is produced via the cytochrome P-450-mediated oxidation pathway in Dendroctonus terebrans body microsomes and rat liver microsomes, and can be further converted into alcohols, ketones and insect pheromone derivatives. α-Pinene oxide can generate the perfume intermediate myrtenal. α-Pinene oxide is used in studies related to terpenoid metabolism and perfume synthesis .
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Hyaluronic acid sodium (MW 800kDa) is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). Hyaluronic acid sodium is synthesized at the plasma membrane. Increased hyaluronic acid sodium levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid sodium participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid sodium activates the PI3K-Akt signaling. Hyaluronic acid sodium acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid sodium can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid sodium can be studied in joint diseases, wound healing and cancer .
Cat. No.: HY-133204R
CAS No.: 71422-67-8
Synonyms: IKI-7899 (Standard)
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Chlorfluazuron (Standard) (IKI-7899 (Standard)) is the analytical standard of Chlorfluazuron (HY-133204). This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea chitin synthesis inhibitor and a PPARγ agonist ligand that blocks the polymerization of UDP-N-acetylglucosamine by inhibiting chitin synthase, disrupting cuticle formation, molting, and embryonic development, thereby exerting ovicidal, larvicidal, and fecundity-reducing effects in insects. Chlorfluazuron is used in hepatotoxicity research .
Cat. No.: HY-B0828S
CAS No.: 1773496-62-0
Synonyms: Hostathion 40EC-d5; Hostathion-d5; Hostation-d5
Cat. No.: HY-E72094
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Human CYP1A2, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 1A2, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP1A2 is a human cytochrome P450 subtype belonging to the CYP1 family, as well as a major metabolic enzyme. Its expression is centered in the human liver, and it can activate procarcinogens including aromatic heterocyclic amines and polycyclic aromatic hydrocarbons .
Cat. No.: HY-E72097
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Human CYP2C8, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2C8, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2C8 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a major metabolic enzyme. It is predominantly expressed in human liver and is capable of metabolizing a variety of active compounds .
Cat. No.: HY-E72098
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Human CYP2C9, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2C9, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2C9 is a human cytochrome P450 subtype belonging to the CYP2 family, and also a major metabolic enzyme. It is predominantly expressed in human liver and can metabolize a variety of active compounds .
Cat. No.: HY-E72102
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Human CYP3A4, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 3A4, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP3A4 is a human cytochrome P450 subtype belonging to the CYP3 family, as well as a major metabolic enzyme. It is predominantly expressed in human liver and intestine, metabolizes a variety of active compounds, and activates multiple procarcinogens .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
