153 Results for "

CGA

" in MedChemExpress (MCE) Product Catalog:
Products (153)

153 Results for "CGA" in MCE Product Catalog:

Cat. No.: HY-B0821R
CAS No.: 123312-89-0
Synonyms: CGA 215944 (Standard)
Research Areas:  

Infection

Pymetrozine (Standard) is the analytical standard of Pymetrozine. This product is intended for research and analytical applications. Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae (Sulzer).
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Cat. No.: HY-162459
CAS No.: 3036368-70-1
Research Areas:  

Inflammation/Immunology

cGAS-IN-3 (compound 30d-S) is an orally active cyclic GMP-AMP synthase (Cyclic GMP-AMP Synthase/cGAS) inhibitor with good plasma exposure and low clearance. cGAS-IN-3 has anti-inflammatory activity and can significantly reduce lung inflammation in rats .
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Cat. No.: HY-B0621R
CAS No.: 68786-66-3
Synonyms: CGA89317 (Standard)
Triclabendazole (Standard) is the analytical standard of Triclabendazole. This product is intended for research and analytical applications. Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME)-dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica .
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Cat. No.: HY-N15159
CAS No.: 146776-30-9
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC50 of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC50 of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria .
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Cat. No.: HY-150747
CAS No.: 1271731-64-6
Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

ODN 6016 is a CpG-A oligonucleotides. ODN 6016 can induce IFN-α production, can be used for researching immune disorders including immunodeficiency caused by HIV-1. ODN 6016 sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G .
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Cat. No.: HY-116214R
CAS No.: 121552-61-2
Synonyms: CGA-219417 (Standard)
Cyprodinil (Standard) (CGA-219417 (Standard)) is the analytical standard of Cyprodinil (HY-116214). This product is intended for research and analytical applications. Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.
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Cat. No.: HY-W681867
CAS No.: 88485-37-4
Synonyms: CGA-133205
Research Areas:  

Others

Fluxofenim (CGA-133205) is a herbicide safener, with activity against Pyroxasulfone (HY-136633) and Metolachlor (HY-B1871). Fluxofenim enhances the activity of needle glutathione S-transferase (GST) towards the substrate 1-chloro-2,4-dinitrobenzene (CDNB) .
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Cat. No.: HY-118578
CAS No.: 57646-30-7
Purity:  99.3%
Synonyms: CGA 38140
Research Areas:  

Infection

Furalaxyl (CGA 38140) is an acylalanine fungicide with high selectivity against the order Peronosporales. Furalaxyl inhibits mycelial growth of Pythium ultimum. Furalaxyl inhibits fungal protein and nucleic acid synthesis, with RNA synthesis being more strongly inhibited than DNA synthesis. The primary mode of action of Furalaxyl is considered to involve impairment of fungal RNA biosynthesis and associated effects on mitosis. Furalaxyl is applicable for studies on oomycete growth inhibition, fungal RNA biosynthesis, and pesticide photodegradation .
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Cat. No.: HY-170362A
CAS No.: 2987886-48-4
Research Areas:  

Inflammation/Immunology

(R)-cGAS-IN-4 (Compound 77A*) is the R-enantiomer of cGAS-IN-4 (HY-170362). cGAS-IN-4 is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS) .
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Cat. No.: HY-179147
CAS No.: 3105027-33-3
Research Areas:  

Inflammation/Immunology

cGAS-IN-6 (14) is a cGAS inhibitor. cGAS-IN-6’s core structure is a fused imidazole ring system. cGAS-IN-6 can be used for research on autoimmune conditions .
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Cat. No.: HY-162966
CAS No.: 3060519-67-4
Research Areas:  

Cancer

MS7829 is a deubiquitinase-targeting chimera (DUBTAC) that targets cGAS. MS7829 recruits OTUB1 to cGAS, binds covalently to OTUB1, stabilizes the protein abundance of cGAS, and activates the cGAS-STING-IRF3 innate immune signaling pathway in an OTUB1-dependent manner. MS7829 is applicable to cancer-related research .
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Cat. No.: HY-RS02577
Research Areas:  

Others

Cgas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cgas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P3864
CAS No.: 133605-57-9
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Pancreastatin (37-52), human is a pancreastatin fragment. Pancreastatin a CgA-derived peptide (CgA residues 250–301) with biological activity, inhibited the releasing of insulin by islet beta cells .
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Cat. No.: HY-150742
CAS No.: 332956-64-6
Research Areas:  

Inflammation/Immunology

ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines .
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Cat. No.: HY-123230S
CAS No.: 2470226-50-5
Synonyms: CGA 279202-d6
Trifloxystrobin-d6 is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h .
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Cat. No.: HY-W020788R
CAS No.: 98730-04-2
Synonyms: CGA 154281 (Standard)
Benoxacor (Standard) is the analytical standard of Benoxacor. This product is intended for research and analytical applications. Benoxacor (CGA 154281) is a herbicide safener and xenobiotic metabolism regulator. Benoxacor protects maize from the toxicity of metolachlor mainly by inducing detoxifying enzymes such as Glutathione S-transferase. Benoxacor also activates FXR, PXR and ERRα, and inhibits aromatase (aromatase). However, Benoxacor exhibits potential subacute oral toxicity and a high risk of hepatotoxicity in animal models. Benoxacor induces reactive oxygen species accumulation, interferes with embryonic heart development, and causes increased liver and kidney weights as well as alterations in gut microbiota in mice. Benoxacor can be used in studies related to hepatic steatosis, infertility, breast cancer and developmental toxicity .
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Cat. No.: HY-115763
CAS No.: 103680-47-3
Synonyms: 3-APPA; CGP 27492; CGA 147823
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of GABA. 3-Aminopropylphosphinic acid is a potent, selective GABAB receptor agonist .
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Cat. No.: HY-150748
CAS No.: 1198621-84-9
Research Areas:  

Inflammation/Immunology Cancer

ODN D-SL01, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. ODN D-SL01 has strong immunostimulatory activity in a variety of vertebrate species and has anticancer activity. ODN D-SL01 sequence: 5'- T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A-3' .
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Cat. No.: HY-W021040R
CAS No.: 131341-86-1
Synonyms: CGA-173506 (Standard)
Research Areas:  

Infection

Fludioxonil (Standard) is the analytical standard of Fludioxonil. This product is intended for research and analytical applications. Fludioxonil, a phenylpyrrole fungicide, has a strong inhibition on mycelia growth of S. sclerotiorum .
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Cat. No.: HY-148412
CAS No.: 864021-55-6
Synonyms: EN101; ODN 7040; BL 7040
Target:  

Cholinesterase (ChE)

Research Areas:  

Others

Monarsen (EN101) is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).
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