203 Results for "

GC

" in MedChemExpress (MCE) Product Catalog:
Products (203)

203 Results for "GC" in MCE Product Catalog:

Cat. No.: HY-130189
CAS No.: 4775-80-8
Purity:  99.38%
Target:  

Drug Metabolite

Research Areas:  

Others

S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay .
loading...
    loading...
Cat. No.: HY-151482
CAS No.: 2768834-39-3
Purity:  98.96%
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent M pro inhibitor (IC50=0.40 μM) with good anti-SARS-CoV-2 activity (EC50=1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies .
loading...
    loading...
Cat. No.: HY-133970
CAS No.: 481-21-0
Purity:  99.34%
5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy .
loading...
    loading...
Cat. No.: HY-114043
CAS No.: 442898-34-2
Purity:  99.54%
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410, a GC chaperone, and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease .
loading...
    loading...
Cat. No.: HY-N6651
CAS No.: 22550-15-8
Isocryptotanshinone is a dual STAT3 and PTP1B (IC50 = 56.1 μM) inhibitor. Isocryptotanshinone inhibits STAT3 by binding to the STAT3 SH2 domain to block phosphorylation and nuclear translocation [1][2]. Isocryptotanshinone exerts its anti-proliferative effect via the induction of cell cycle arrest, apoptosis, and pro-death autophagy, through the regulation of STAT3, AKT/mTOR and MAPK signaling pathways. Isocryptotanshinone suppresses the xenograft gastric cancer (GC) tumor growth in BALB/c nude mice. Isocryptotanshinone can be used for cancer research, such as lung cancer, breast cancer and GC .
loading...
    loading...
Cat. No.: HY-149453
CAS No.: 2747162-85-0
Purity:  99.85%
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy .
loading...
    loading...
Cat. No.: HY-N10220
CAS No.: 125600-53-5
Paraherquamide E is a paraherquamide alkaloid and 14C-deshydroxy paraherquamide analog found in Aspergillus aculeatus GC-147‑5 and Penicillium charlesii, with insecticidal and reproductive toxicant activity, high selectivity, and negligible toxicity to nontarget ladybugs .Paraherquamide E disrupts fatty acid synthesis, inhibits vitellogenin production, alters metabolic homeostasis, induces ovarian abnormalities, and causes Asian citrus psyllid mortality, while remaining inactive against Asian citrus psyllid cholinergic systems .
loading...
    loading...
Cat. No.: HY-P991571
Synonyms: GC-1118A

Target:  

EGFR PERK Akt

Research Areas:  

Cancer

GC1118 (GC-1118A) is a fully human anti-EGFR monoclonal antibody with binding affinity of 0.16 nM (KD) to EGFR. GC1118 displays potent inhibitory effects on high- and low-affinity EGFR ligand-induced signaling. GC1118 shows potent anti proliferative activity in KRAS wild-type and KRAS mutant cells. GC1118 can reach the tumor by crossing both BBB (blood-brain barrier) and BTB (brain-tumor barrier) and shows superior anti-tumor effects in various mice xenograft models. GC1118 can be used for the researches of cancer, such as colorectal cancer .
loading...
    loading...
Cat. No.: HY-108314
CAS No.: 150333-69-0
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
loading...
    loading...
Cat. No.: HY-14823G
CAS No.: 211110-63-3
Synonyms: GC-1 (GMP); QRX-431 (GMP)
Sobetirome (GMP) is Sobetirome (HY-14823) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC50 of 0.16 μM .
loading...
    loading...
Cat. No.: HY-130189R
CAS No.: 4775-80-8
Research Areas:  

Others

S-Phenylmercapturic acid (Standard) is the analytical standard of S-Phenylmercapturic acid. This product is intended for research and analytical applications. S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay .
loading...
    loading...
Cat. No.: HY-132829
CAS No.: 2248030-85-3
Synonyms: GC4711
Research Areas:  

Cancer

Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-131389
CAS No.: 24365-37-5
Purity:  ≥98.0%
Research Areas:  

Others

Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
loading...
    loading...
Cat. No.: HY-N10626
CAS No.: 125139-41-5
Neu5Gcα(2-6) N-Glycan is an glycan. Neu5Gcα(2-6) N-Glycan can be used for the various biochemical studies .
loading...
    loading...
Cat. No.: HY-111442
CAS No.: 447415-34-1
Research Areas:  

Metabolic Disease

GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTRβ and hTRα, respectively.
loading...
    loading...
Cat. No.: HY-N15820
CAS No.: 3056013-75-0
Category:  

Lipids

C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) is a ganglioside.
loading...
    loading...
Cat. No.: HY-N15822
CAS No.: 851608-39-4
Category:  

Lipids

C18:0 GM3(Neu5Gc) Ceramide (d18:1/18:0) is a sphingolipid.
loading...
    loading...
Cat. No.: HY-160180
CAS No.: 3014393-37-1
Glucocorticoid receptor agonist-4 Ala-Ala-Mal (Compound Preparation 9) is an anti-human TNFα antibody-glucocorticoid receptor agonist (GC) conjugate. Glucocorticoid receptor agonist-4 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases .
loading...
    loading...
Cat. No.: HY-141642
CAS No.: 2438-40-6
Purity:  ≥98.0%
Synonyms: Glycerol triheptadecanoate; Trimargarin
Research Areas:  

Others

Triheptadecanoin (Glycerol triheptadecanoate) is an internal standard for the rapid GC analysis of fatty acid methyl esters in edible fats and oils. Triheptadecanoin enables the quantitative analysis of trans-fatty acid content in edible fats and oils via a rapid GC method. Triheptadecanoin smoothly undergoes methylation with m-TFPTAH in toluene solution at room temperature .
loading...
    loading...
Cat. No.: HY-P0118A
Synonyms: P144 TFA
Research Areas:  

Cancer

Disitertide (P144) TFA is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide TFA is also a PI3K inhibitor and an apoptosis inducer .
loading...
    loading...