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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
KDM4
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "KDM4" in MCE Product Catalog:
Cat. No.: HY-101928R
CAS No.: 2098902-68-0
Research Areas:
KDM4D-IN-1 (Standard) is the analytical standard of KDM4D-IN-1 (HY-101928). This product is intended for research and analytical applications. KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
Cat. No.: HY-RS17132
Target:
Research Areas:
Kdm4b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kdm4b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17833
Target:
Research Areas:
Kdm4c Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kdm4c gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24301
Target:
Research Areas:
Kdm4c Rat Pre-designed siRNA Set A contains three designed siRNAs for Kdm4c gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101799R
CAS No.: 2003260-55-5
Synonyms: KDM4B Inhibitor B3 (Standard)
Research Areas:
NCGC00244536 (Standard) (KDM4B Inhibitor B3 (Standard)) is the analytical standard of NCGC00244536 (HY-101799). This product is intended for research and analytical applications. NCGC00244536 is a potent KDM4B inhibitor with an IC50 of 10 nM.
Cat. No.: HY-125243
CAS No.: 2281766-67-2
Target:
Research Areas:
KDM5A-IN-2 is a KDM5A inhibitor. The human IC50 values of KDM5A-IN-2 for KDM5A, KDM5B, and KDM4A are 0.11 μM, 0.22 μM, and 5.3 μM, respectively. KDM5A-IN-2 inhibits KDM5B- and KDM4A-mediated histone lysine demethylation .
Cat. No.: HY-183928
CAS No.: 1503332-97-5
Target:
Research Areas:
EPZ020809 is a competitive KDM4C inhibitor with a Ki of 31 nM .
Cat. No.: HY-P83586A
Synonyms: KDM4A; JHDM3A; JMJD2; JMJD2A; KIAA0677; Lysine-specific demethylase 4A; JmjC domain-containing histone demethylation protein 3A; Jumonji domain-containing protein 2A
Cat. No.: HY-183618
Target:
Research Areas:
DW-229 is a PROTAC degrader derived from Deferiprone (HY-B0568), targeting Fe(II)/α‑ketoglutarate‑dependent histone lysine demethylases (KDMs). DW-229 degrades KDM2A, KDM3A, KDM5B, KDM4A‑C, KDM5C, KDM6B in breast cancer cells. DW-229 shows IC50 < 0.5 μM against MCF‑7 cells and IC50 of 8.87 μM against MDA‑MB‑231 cells, with high cancer cell selectivity. DW-229 can be used for the research of breast cancer, liver cancer, prostate cancer, lung cancer .
Cat. No.: HY-P703619
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM4C; Jumonji Domain-Containing Protein 2C; Prev. JMJD2C; Lysine-Specific Demethylase 4C; GASC1; Tudor Domain Containing 14C; KIAA0780; JHDM3C; TDRD14C; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase; JmjC Domain-Containing Histone Demethylation Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P702951
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDM4C; Jumonji Domain-Containing Protein 2C; Prev. JMJD2C; Lysine-Specific Demethylase 4C; GASC1; Tudor Domain Containing 14C; KIAA0780; JHDM3C; TDRD14C; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase; JmjC Domain-Containing Histone Demethylation Protein
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701618
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM4A; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase 4A; Prev. JMJD2A; Lysine (K)-Specific Demethylase 4A; Prev. JMJD2; Lysine-Specific Demethylase 4A; JHDM3A; Jumonji Domain Containing 2A; KIAA0677; Tudor Domain Containing 14A; TDRD14A; Jumonji Domain C
Species:
Human
Source:
E. coli
Cat. No.: HY-P701619
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM4A; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase 4A; Prev. JMJD2A; Lysine (K)-Specific Demethylase 4A; Prev. JMJD2; Lysine-Specific Demethylase 4A; JHDM3A; Jumonji Domain Containing 2A; KIAA0677; Tudor Domain Containing 14A; TDRD14A; Jumonji Domain C
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
