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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
332 Results for "
Substrate specificity
" in MedChemExpress (MCE) Product Catalog:
Products (332)
332 Results for "Substrate specificity" in MCE Product Catalog:
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1 Cited Publications
Art. -Nr.: HY-W012985
CAS. Nr.: 600-22-6
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Methyl pyruvate is a p53/p21 axis inhibitor, intrinsic apoptosis inhibitor, cytotoxic agent, ATP production enhancer, proteasome function restorer, TDP-43 localization normalizer, ATP-sensitive potassium (K +ATP) channel inhibitor, depolarizer, and insulin secretagogue .Methyl pyruvate turns off apoptotic pathways, induces cancer cell death, acts as a substrate for dimeric dihydrodiol dehydrogenase, enhances TCA cycle activity, rescues proteasome impairment and TDP-43 mislocalization, inhibits K +ATP channels independent of ATP, depolarizes pancreatic β-cell membranes, modulates insulin secretion, and enters pancreatic β-cell mitochondria via a specific transporter .Methyl pyruvate can be used for the research of lung adenocarcinoma, ovarian clear cell adenocarcinoma, breast adenocarcinoma, amyotrophic lateral sclerosis, and type II diabetes .
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Methyl α-D-mannopyranoside (α-Methyl-D-mannoside) is a methyl glycoside derivative and conformational stabilizer of α-D-mannopyranose. The glycosidic bond conformation of Methyl α-D-mannopyranoside is significantly affected by the environment. In aqueous solution, Methyl α-D-mannopyranoside stabilizes into a trans conformation via intermolecular hydrogen bonds; in the gas phase, however, steric interactions drive Methyl α-D-mannopyranoside to prefer a clockwise gauche conformation. Methyl α-D-mannopyranoside also serves as a major component of secondary cell wall polymers in some bacteria and an active precursor site for virus-targeted glycoproteins. Methyl α-D-mannopyranoside acts as an acceptor substrate for alternansucrase, mediating the transfer of D-glucopyranosyl groups to generate a variety of glycosylated oligosaccharide products, with methyl α-D-glucopyranosyl-(1→6)-α-D-mannopyranoside as the main component. Methyl α-D-mannopyranoside is applicable to studies on bacterial pathogenic mechanisms associated with mannose-specific fimbrial lectins .
Art. -Nr.: HY-W009004
CAS. Nr.: 13184-14-0
Synonyms: Lys-Lys-Lys; H-Lys-Lys-Lys-OH
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Art. -Nr.: HY-P3949
CAS. Nr.: 143147-75-5
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Art. -Nr.: HY-P5990
CAS. Nr.: 380225-52-5
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Art. -Nr.: HY-P5979
CAS. Nr.: 1071466-49-3
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Art. -Nr.: HY-P10602
CAS. Nr.: 103659-06-9
Synonyms: RII phosphopeptide
Art. -Nr.: HY-P0266
CAS. Nr.: 127103-11-1
Synonyms: Ac-SdKP
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Ac-PAL-AMC is a fluorogenic substrate specific for 20S proteasome LMP2/β1i activity .
Art. -Nr.: HY-W718137
CAS. Nr.: 66927-03-5
Art. -Nr.: HY-P2016
CAS. Nr.: 355140-49-7
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Art. -Nr.: HY-P4426A
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Art. -Nr.: HY-U00452
CAS. Nr.: 1456872-74-4
Art. -Nr.: HY-W039915
CAS. Nr.: 48149-72-0
Art. -Nr.: HY-P5430
CAS. Nr.: 2250228-51-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
