Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
265 Results for "
TRAP
" in MedChemExpress (MCE) Product Catalog:
Products (265)
265 Results for "TRAP" in MCE Product Catalog:
Target:
Research Areas:
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .
Cat. No.: HY-P1000
CAS No.: 137339-65-2
Synonyms: SFLLRNPNDKYEPF
Target:
Research Areas:
Synonyms: DNS-glutathione
Target:
Research Areas:
Dansyl glutathione is a trapping agent for the quantitative estimation and identification of reactive metabolites.
Target:
Research Areas:
TRAP1-IN-1 (compound 35) is a potent and selective inhibitor of TRAP1，a mitochondrial isoform of Hsp90. TRAP1-IN-1 has >250-fold TRAP1 selectivity over Grp94，and disrupts TRAP1 tetramer stability，induces TRAP1 client protein degradation. TRAP1-IN-1 also inhibits mitochondrial complex I of oxidative phosphorylation OXPHOS，disrupts the mitochondrial membrane potential，and enhances glycolysis metabolism .
Cat. No.: HY-169369
CAS No.: 3109600-48-5
Synonyms: XJZ-06-462
TRAP-1 (XJZ-06-462) is a transcriptional activator of p53 (TRAP) with JQ-1 carboxylic acid (HY-78695) as its target protein ligand. TRAP-1 forms a ternary complex with p53 Y220C and BRD4, potently activates p53 transcription, and inhibits the growth and proliferation of tumor cells. TRAP-1 upregulates p21 and other p53 target genes in pancreatic cell lines carrying p53 Y220C, and induces cellular senescence and apoptosis. TRAP-1 can be used in cancer research involving p53 Y220C-carrying tumors .
Synonyms: 4-POBN
Target:
Research Areas:
POBN (4-POBN) is a cell permeable, hydrophilic spin trap that can be used to detect free radical adducts .
Cat. No.: HY-P2321
CAS No.: 141923-40-2
Research Areas:
TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide .
Target:
Research Areas:
AubipyOMe serves as a potent inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme found in activated osteoclasts and macrophages, demonstrating IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, while effectively inhibiting TRAP activity in extracts from murine macrophages and human lung tissue.
Cat. No.: HY-P4373
CAS No.: 1676104-75-8
Research Areas:
Cat. No.: HY-15595
CAS No.: 794458-56-3
Target:
Research Areas:
360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.
Cat. No.: HY-P4987
CAS No.: 145229-76-1
Research Areas:
Cat. No.: HY-P5001
CAS No.: 150242-29-8
Synonyms: iso-SFLLRN
Research Areas:
Cat. No.: HY-124663
CAS No.: 1212663-24-5
Research Areas:
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV, TRAP 5b OX and TRAP 5a OX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively .
Cat. No.: HY-P5359
CAS No.: 141136-84-7
Synonyms: TRAP-6 (2-6)
Research Areas:
Cat. No.: HY-RS17325
Target:
Research Areas:
Acp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-136501
CAS No.: 491611-55-3
Target:
Research Areas:
MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6 .
Cat. No.: HY-RS00190
Target:
Research Areas:
ACP5 Human Pre-designed siRNA Set A contains three designed siRNAs for ACP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1536
CAS No.: 141685-53-2
Research Areas:
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
