1. Anti-infection
  2. Fungal

AN2718 

Cat. No.: HY-100527
Handling Instructions

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

For research use only. We do not sell to patients.

AN2718 Chemical Structure

AN2718 Chemical Structure

CAS No. : 174672-06-1

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10 mg USD 70 Get quote
25 mg USD 120 Get quote
50 mg USD 190 Get quote
100 mg USD 290 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

IC50 & Target

Fungal[1].

In Vitro

AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus, and from yeasts, C. albicans, with an IC50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T.mentagrophytes[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9386 mL 29.6930 mL 59.3859 mL
5 mM 1.1877 mL 5.9386 mL 11.8772 mL
10 mM 0.5939 mL 2.9693 mL 5.9386 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

168.39

Formula

C₇H₆BClO₂

CAS No.

174672-06-1

SMILES

OB1OCC2=CC(Cl)=CC=C21

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
AN2718
Cat. No.:
HY-100527
Quantity:

AN2718

Cat. No.: HY-100527