Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
642 Results for "
4a
" in MedChemExpress (MCE) Product Catalog:
Products (642)
642 Results for "4a" in MCE Product Catalog:
Cat. No.: HY-103090A
CAS No.: 1781934-44-8
Target:
Research Areas:
NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
Cat. No.: HY-19557
CAS No.: 1251165-81-7
Target:
Research Areas:
IDX-320 is a Pipecolic acid (HY-Y0669) derivative. IDX-320 inhibits NS3/4a proteases across genotypes 1a, 1b, 2a, and 4a with an IC50 0.8-1.9 nM. IDX-320 can be used in the research of HCV infection .
Target:
Research Areas:
4-Propionamidophenol (compound 4a) is an inactive estrogen receptor ligand based on the diphenylamine skeleton .
Cat. No.: HY-14404
CAS No.: 924270-31-5
Target:
Research Areas:
MK-1220 is a covalently reversible inhibitor of the hepatitis C virus (HCV) NS3/4A protease (NS3/4A protease) with a Ki of 0.02 nM. MK-1220 in cell models simulating viral replication exhibits EC50s of 4 (with 10% fetal bovine serum) and 11 nM (50% normal human serum). MK-1220 can be used for the study of chronic hepatitis C virus infection .
Cat. No.: HY-131905S
CAS No.: 1606150-08-6
Cat. No.: HY-108473R
CAS No.: 1279713-77-7
Synonyms: TLR3-IN-1 (Standard)
Research Areas:
CU-CPT 4a (Standard) is the analytical standard of CU-CPT 4a (HY-108473). This product is intended for research and analytical applications. CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β .
Cat. No.: HY-P990236
Target:
Research Areas:
Cat. No.: HY-N10922
CAS No.: 878800-84-1
Target:
Cat. No.: HY-E71239A
Target:
Research Areas:
α-Glucuronidase 4A, Thermotoga maritima (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O ? an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. α-Glucuronidase 4A, Thermotoga maritima (EC 3.2.1.139) belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O-and S-glycosyl compounds.
Cat. No.: HY-10038R
CAS No.: 959122-11-3
Synonyms: DGAT-1 Inhibitor 4a (Standard)
Target:
Research Areas:
A 922500 (Standard) is the analytical standard of A 922500 (HY-10038). This product is intended for research and analytical applications. A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of 9 and 22 nM against human and mouse DGAT-1, respectively.
Cat. No.: HY-N10683
CAS No.: 268541-27-1
Target:
Cat. No.: HY-Z8472
CAS No.: 77517-29-4
Synonyms: Lovastatin EP impurity E; 4a,5-Dihydromevinolin
Category:
Cat. No.: HY-172900
AKT-IN-27 (4a) is a potential anticancer agent through selective therapeutic targeting of Akt-driven pathways. AKT-IN-27 (4a) induces apoptosis via caspase-3 activation, G2/M cell cycle arrest, and mitochondrial membrane potential disruption. AKT-IN-27 (4a) can be used in the research for TNBC (triple-negative breast cancer) .
Cat. No.: HY-P10608
CAS No.: 851626-94-3
Cat. No.: HY-43913
CAS No.: 2095484-82-3
Research Areas:
(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM .
Cat. No.: HY-145359
CAS No.: 2100145-31-9
Research Areas:
eIF4A3-IN-5 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-5 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) .
Cat. No.: HY-E71231
Target:
Research Areas:
α-Galactosidase 4A, Bacillus halodurans (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .
Cat. No.: HY-116380
CAS No.: 1314230-69-7
Target:
Research Areas:
CB2 receptor antagonist 5 (compound 4A) is a ligand of CB2 receptor with antagonist effect .
Cat. No.: HY-W994722
CAS No.: 473707-40-3
ISO24 (compound 4a) is a potent liagnd of Src SH2, with the IC50 of 4.4 mM in BIAcore assay .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
