Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
394 Results for "
monkey FAP
" in MedChemExpress (MCE) Product Catalog:
Products (394)
394 Results for "monkey FAP" in MCE Product Catalog:
Cat. No.: HY-175350
CAS No.: 2688118-55-8
Synonyms: OncoFAP glidotin
Target:
Research Areas:
OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. OncoFAP-GlyPro-MMAE consists of a FAP Ligand OncoFAP (HY-145938), a Tubulin inhibitor (MMAE) (HY-15162) and a linker. OncoFAP-GlyPro-MMAE can be used for cancers like renal cancer research .
Cat. No.: HY-P990136
Target:
Research Areas:
Anti-Monkey/Human CD28 Antibody (CD28.2) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to monkey/human CD28. Anti-Monkey/Human CD28 Antibody (CD28.2) can block CD28 signaling. Anti-Monkey/Human CD28 Antibody (CD28.2) can be used for the research of immunology .
Cat. No.: HY-P990189
Cat. No.: HY-NP002O
Synonyms: Cynomolgus monkey serum albumin
Target:
Research Areas:
CMSA Protein (Cynomolgus Monkey Serum Albumin) is a plasma protein derived from cynomolgus monkeys. It is highly homologous to HSA (HY-P1956) and has an extremely high sequence similarity. CMSA Protein mainly regulates blood osmotic pressure and binds or transports hormones, metals, and active compounds.
Cat. No.: HY-RS29457
Target:
Research Areas:
TMEM175 Monkey Pre-designed siRNA Set A contains three designed siRNAs for TMEM175 (Monkey), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
TMEM175 siRNA-1: 5 nmol (HPLC)
TMEM175 siRNA-2: 5 nmol (HPLC)
TMEM175 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Components
TMEM175 siRNA-1: 5 nmol (HPLC)
TMEM175 siRNA-2: 5 nmol (HPLC)
TMEM175 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Cat. No.: HY-177083
CAS No.: 1841402-73-0
Synonyms: AVA-6000
Faridoxorubicin (AVA-6000) is a FAP-activated chemotherapeutic prodrug. Faridoxorubicin undergoes selective hydrolysis by FAP, while it is resistant to cleavage by related mammalian peptidases and members of the DASH subfamily. Faridoxorubicin acts as a tumor growth inhibitor, reducing tumor volume and prolonging survival in in vivo models and PDX models with high FAP expression. Faridoxorubicin can be used in the research of osteosarcoma and sarcoma .
Cat. No.: HY-164725
CAS No.: 3023869-94-2
Research Areas:
Cat. No.: HY-P990196
Target:
Research Areas:
Cat. No.: HY-175685
CAS No.: 3020777-28-7
FAP-IN-7 (Compound 5b) is a FAPFAP-IN-7 labeled with 18F enhances tumor retention with high selectivity and favorable pharmacokinetics. FAP-IN-7 can be used as a radiotracer for PET imaging and radionuclide therapy of cancers research .
Cat. No.: HY-147057A
Synonyms: FAP-2286 acetate
Rofapitide tetraxetan (FAP-2286) acetate is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan acetate can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan acetate has antitumor activity .
Cat. No.: HY-145358
CAS No.: 2415941-98-7
FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .
Cat. No.: HY-RS29446
Target:
Research Areas:
ATP6V1A Monkey Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1A gene (Monkey), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5049
CAS No.: 17750-75-3
Target:
Research Areas:
Cat. No.: HY-W668749
CAS No.: 2374782-82-6
Target:
Research Areas:
3BP-3580 (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 can be used for research on rheumatoid arthritis .
Cat. No.: HY-175353
TriOncoFAP-GlyPro-MMAE is a small molecule drug conjugate (SMDC) targeting fibroblast activation protein (FAP) with an IC50 of 13 pmol/L. TriOncoFAP-GlyPro-MMAE combines a FAP-targeting ligand (TriOnco), a cleavable glycine-proline linker, and a cytotoxic payload (MMAE) .
Cat. No.: HY-174421
FAPI-JNU is a molecule targeting fibroblast activation protein (FAP). FAPI-JNU specifically binds to FAP highly expressed in the tumor microenvironment, and uses radionuclides [ 68Ga]Ga or [ 177Lu]Lu to achieve tumor imaging diagnosis. [177Lu]Lu−FAPI−JNU can effectively target and inhibit tumor growth in tumor-bearing mice. FAPI-JNU is promising for research of FAP-positive tumors (such as various solid tumors) .
Cat. No.: HY-175612
DOTA-ALB-01 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-01 labeled with 68Ga or 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention. DOTA-ALB-01 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
