247 Results for "

translational diffusion coefficient

" in MedChemExpress (MCE) Product Catalog:
Products (247)

247 Results for "translational diffusion coefficient" in MCE Product Catalog:

Cat. No.: HY-18078
CAS No.: 927691-21-2
Research Areas:  

Neurological Disease

PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A) with IC50 andED50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia .
loading...
    loading...
Cat. No.: HY-150759
CAS No.: 2677762-43-3
Purity:  99.54%
Target:  

HIV

Research Areas:  

Infection

HIV-1 inhibitor-45 is a potent HIV-1 RNase H inhibitor with an IC50 value of 0.067 μM. HIV-1 inhibitor-45 shows an antiviral activity. HIV-1 inhibitor-45 shows poor cell permeability (with an apparent permeability coefficient (Papp) lower than 0.48 × 10 −6 cm/s) .
loading...
    loading...
Cat. No.: HY-W581820
CAS No.: 10030-90-7
Synonyms: Ferrous succinate
Research Areas:  

Cardiovascular Disease

Iron(II) succinate (Ferrous succinate) is an orally active and organic acid iron supplement (ferrous salt). Iron(II) succinate improves hematological parameters in iron-deficiency anemia rats, including hemoglobin, red blood cells, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. Iron(II) succinate increases serum ferritin, serum iron levels, and transferrin saturation, while decreasing total iron-binding capacity in iron-deficiency anemia rats. Iron(II) succinate reduces the elevated heart, spleen, and kidney coefficients, and increases the decreased liver coefficient in iron-deficiency anemia rats. Iron(II) succinate replenishes the depleted iron content in the liver and spleen of iron-deficiency anemia rats. Iron(II) succinate can be used for the research of iron-deficiency anemia .
loading...
    loading...
Cat. No.: HY-W014930R
CAS No.: 13204-98-3
DL-5-Hydroxylysine (hydrochloride) (Standard) is the analytical standard of DL-5-Hydroxylysine (hydrochloride). This product is intended for research and analytical applications. DL-5-Hydroxylysine hydrochloride is a non-essential amino acid that is mainly found in collagen. DL-5-Hydroxylysine hydrochloride is a post-translational modified form of lysine .
loading...
    loading...
Cat. No.: HY-W134328B
CAS No.: 87915-38-6
Synonyms: Dextran blue (MW 10000)
Blue dextran (Dextran blue) (MW 10000) is a 10 kDa osmotic dextran. Blue dextran (MW 10000) penetrates all sublayers of the pre-epithelial mucus gel layer in the rat distal colon and is taken up by the nuclei of surface cells in the rat distal colonic mucosa. Blue dextran (MW 10000) is not blocked by the pre-epithelial mucus gel layer of the rat distal colon, which acts as a diffusion barrier .
loading...
    loading...
Cat. No.: HY-34544
CAS No.: 18794-77-9
2-Hexylthiophene is an extremely weak basic heteroaromatic compound. 2-Hexylthiophene can be used to modify and improve the molar absorption coefficient of ruthenium sensitizer
loading...
    loading...
Cat. No.: HY-19804A
Photo-lysine hydrochloride, a new lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications.
loading...
    loading...
Cat. No.: HY-N4236
CAS No.: 19625-17-3
Angelol A is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
loading...
    loading...
Cat. No.: HY-N15738
CAS No.: 110715-67-8
(-)-Zonarol is an antifungal agent. (-)-Zonarol exhibits divergent translational potential. (-)-Zonarol is an isomer of Zonarol. Zonarol is a (-)-Yahazunol-related natural product .
loading...
    loading...
Cat. No.: HY-N4235
CAS No.: 83156-04-1
Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
loading...
    loading...
Cat. No.: HY-177963
CAS No.: 2341941-41-9
Target:  

DNA Methyltransferase

Research Areas:  

Inflammation/Immunology

NV914 is an inhibitor of FTSJ1 (tryptophan tRNA-specific 2'-O-methyltransferase) that inhibits the methyltransferase activity of FTSJ1, induces translational readthrough of premature termination codons, and enables genes carrying nonsense mutations to synthesize full-length proteins. NV914 belongs to translational readthrough-inducing compounds (TRIDs). NV914 exhibits translational readthrough activity against nonsense mutations in in vitro systems, does not induce readthrough of natural termination codons, and restores CFTR protein expression. NV914 shows favorable acute oral tolerance in mice, with low health risks and good safety profiles. NV914 is applicable to research related to cystic fibrosis and Shwachman-Diamond syndrome .
loading...
    loading...
Cat. No.: HY-103467
CAS No.: 223759-19-1
Target:  

Fluorescent Dye

Research Areas:  

Others

NPE-caged-HPTS sodium is a caged fluorophore that fluoresces upon uncaged fluorophore release, releasing the free highly polar fluorophore HPTS (Exc=470/40 nm, Em=525/50 nm). HPTS releases the fluorophore rapidly and uniformly, allowing for measurement of diffusion within tissues, with a diffusion coefficient of μm 2s -1, similar to that of synaptic L-glutamate .
loading...
    loading...
Cat. No.: HY-114005
CAS No.: 607368-97-8
Target:  

CMV

Research Areas:  

Infection

SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications .
loading...
    loading...
Cat. No.: HY-D2283
Photo-DL-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
loading...
    loading...
Cat. No.: HY-N10273
CAS No.: 156856-32-5
Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .
loading...
    loading...
Cat. No.: HY-120316
CAS No.: 139159-01-6
Target:  

Parasite

Research Areas:  

Infection

AB3127-C is an anti-mite agent that can be isolated from Streptomyces platensis AB3217. AB3127-C exerts a protection coefficient of 90% at a concentration of 100 μg/mL .
loading...
    loading...
Cat. No.: HY-113230
CAS No.: 32448-36-5
Galactosylhydroxylysine is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine is released during bone resorption and has been shown to be elevated in metabolic bone loss .
loading...
    loading...
Cat. No.: HY-W641657
CAS No.: 2095-20-7
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Desmonomethylpromazine is the brain-penetrant demethylated metabolite of Promazine (HY-B1225A). Desmonomethylpromazine can enter red blood cells and tissues through passive diffusion, distributes in tissues such as lung, liver, and kidney in rats .
loading...
    loading...
Cat. No.: HY-157140
CAS No.: 1644442-22-7
Research Areas:  

Others

HibK is is a new type of histone mark that is widely distributed in histone proteins. HibK as a useful tool can be used for probing post-translational modification by site-specifically incorporate HibK into proteins .
loading...
    loading...
Cat. No.: HY-D2283S1
Photo-lysine-d2 is the deuterium labeled Photo-lysine. Photo-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
loading...
    loading...