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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
907 Results for "
Inactive
" in MedChemExpress (MCE) Product Catalog:
Products (907)
907 Results for "Inactive" in MCE Product Catalog:
Cat. No.: HY-P7725
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA10; Carbonic Anhydrase-Related Protein X; Carbonic Anhydrase 10 (Inactive); Carbonic Anhydrase X; Carbonic Anhydrase-Related Protein 10; CA-RP X; Carbonic Anhydrase 10; CARP X; HUCEP-15; Epididymis Secretory Sperm Binding Protein; CA-RPX; Cerebral Prote
Species:
Human
Source:
E. coli
Cat. No.: HY-P71559
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NAALADL2; NAALADase L2; N-Acetylated Alpha-Linked Acidic Dipeptidase Like 2; N-Acetylated Alpha-Linked Acidic Dipeptidase 2; Inactive N-Acetylated-Alpha-Linked Acidic Dipeptidase-Like Protein 2; Putative NAALADL2 Protein; Glutamate Carboxypeptidase II-Typ
Species:
Human
Source:
E. coli
Cat. No.: HY-P72864
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA10; Carbonic Anhydrase-Related Protein X; Carbonic Anhydrase 10 (Inactive); Carbonic Anhydrase X; Carbonic Anhydrase-Related Protein 10; CA-RP X; Carbonic Anhydrase 10; CARP X; HUCEP-15; Epididymis Secretory Sperm Binding Protein; CA-RPX; Cerebral Prote
Species:
Human
Source:
HEK293
Cat. No.: HY-P77151
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIL2; PPIase; Peptidylprolyl Isomerase Like 2; Peptidylprolyl Isomerase (Cyclophilin)-Like 2, Isoform CRA_d; CYC4; RING-Type E3 Ubiquitin Transferase Isomerase-Like 2; Probable Inactive Peptidyl-Prolyl Cis-Trans Isomerase-Like 2; Nitric Oxide Synthase-In
Species:
Human
Source:
E. coli
Cat. No.: HY-P703360
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK4; WNK Lysine Deficient Protein Kinase 4; PRKWNK4; Serine/Threonine-Protein Kinase WNK4; Protein Kinase Lysine-Deficient 4; Protein Kinase With No Lysine 4; Protein Kinase, Lysine Deficient 4; PHA2B
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-112306R
CAS No.: 1442472-39-0
Synonyms: DCC-2618 (Standard)
Ripretinib (Standard) is the analytical standard of Ripretinib. This product is intended for research and analytical applications. Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2) . DCC-2618 exerts antineoplastic effect and induces apoptosis .
Cat. No.: HY-113293S1
Target:
Cat. No.: HY-12028R
CAS No.: 167869-21-8
Research Areas:
PD98059 (Standard) is the analytical standard of PD98059. This product is intended for research and analytical applications. PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy .
Category:
Cat. No.: HY-162895
NL13 is a Polo-like kinase 4 (PLK4) inhibitor with an IC50 value of 2.32 μM. NL13 can inhibit the viability of PC3 and DU145 prostate cancer cells, with IC50 values of 3.51 μM and 2.53 μM, respectively. NL13 can lead to the inactivation of the AKT signaling pathway by downregulating CCNB1/CDK1, inducing G2/M cell cycle arrest, and triggering apoptosis through the cleavage of caspase-9/caspase-3. In prostate cancer mice, NL13 can inhibit tumor growth .
Cat. No.: HY-B0579S3
Synonyms: Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4; CsA-13C2,d4
Cat. No.: HY-B1128
CAS No.: 34444-01-4
Synonyms: Cephamandole
Target:
Research Areas:
Cefamandole (Cephamandole) is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole is widely used in studies related to bacterial infections .
Cat. No.: HY-B1128A
CAS No.: 30034-03-8
Synonyms: Cephamandole sodium
Target:
Research Areas:
Cefamandole (Cephamandole) sodium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole sodium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole sodium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole sodium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole sodium is widely used in studies related to bacterial infections .
Cat. No.: HY-N8380
CAS No.: 10154-42-4
Category:
Target:
Cat. No.: HY-106991
CAS No.: 878189-87-8
Synonyms: S-303
Target:
Research Areas:
Amustaline (S-303) is a compound used for inactivating pathogens in blood components and belongs to the category of nucleic acid-targeted chemical decontaminants. Amustaline has the ability to inactivate viruses and is effective against mosquito-borne viruses such as Chikungunya virus (CHIKV), Dengue virus (DENV), and Zika virus (ZIKV). When combined with glutathione (Glutathione, GSH), which acts as a neutralizer to counteract adverse reactions, Amustaline ensures the stability of red blood cell membranes. Amustaline is mainly used for inactivating pathogens in red blood cell concentrates (RBCC) to reduce the risk of transfusion-transmitted infections (TTI) .
Cat. No.: HY-P7724
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA10; Carbonic Anhydrase-Related Protein X; Carbonic Anhydrase 10 (Inactive); Carbonic Anhydrase X; Carbonic Anhydrase-Related Protein 10; CA-RP X; Carbonic Anhydrase 10; CARP X; HUCEP-15; Epididymis Secretory Sperm Binding Protein; CA-RPX; Cerebral Prote
Species:
Human
Source:
HEK293
Cat. No.: HY-P72865
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA10; Carbonic Anhydrase-Related Protein X; Carbonic Anhydrase 10 (Inactive); Carbonic Anhydrase X; Carbonic Anhydrase-Related Protein 10; CA-RP X; Carbonic Anhydrase 10; CARP X; HUCEP-15; Epididymis Secretory Sperm Binding Protein; CA-RPX; Cerebral Prote
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P74409
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ART3; Ecto-ADP-Ribosyltransferase 3; ADP-Ribosyltransferase 3 (Inactive); Mono-ADP-Ribosyltransferase; ARTC3; NAD(P)(+)--Arginine ADP-Ribosyltransferase; ADP-Ribosyltransferase C2 And C3 Toxin-Like 3; Mono(ADP-Ribosyl)Transferase; NAD(P)(+)--Arginine ADP-
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
