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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1041 Results for "
detection
" in MedChemExpress (MCE) Product Catalog:
Products (1041)
1041 Results for "detection" in MCE Product Catalog:
Cat. No.: HY-D3124
Target:
Research Areas:
Gol-SiRhoNox is a Golgi apparatus-targeted fluorescent probe with high selectivity for Fe (II), with a limit of detection of 50 nM. Gol-SiRhoNox integrates a myristoyl motif for Golgi apparatus targeting and a silicon-fused rhodamine N-oxide as the Fe (II)-sensitive moiety. Gol-SiRhoNox is non-fluorescent in its native state; Fe (II)-mediated deoxygenation of the N-oxide triggers fluorescence recovery. Its fluorescent product, Gol-SiR, has excitation/emission wavelengths of 630/665 nm and a maximum absorption wavelength of 655 nm .
Cat. No.: HY-D3136
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MC-PSE is a fluorescent probe that can be used for glutathione (GSH) detection, NIR-II fluorescence imaging and ratiometric photoacoustic imaging. MC-PSE spontaneously forms J-aggregates in aqueous solution through π-π stacking, and its phenylselenyl group acts as a fluorescence quencher and GSH recognition receptor, thereby eliminating intrinsic fluorescence and generating a maximum absorption peak at 1000 nm. The excitation/emission wavelengths of MC-PSE are Ex = 808 nm and Em = 940 nm. MC-PSE can be applied in tumor-related research .
Cat. No.: HY-D3269
CAS No.: 2088127-60-8
Cat. No.: HY-D3405
CAS No.: 173357-16-9
Cat. No.: HY-DY1019
CAS No.: 186689-07-6
Solvent and Concentration: Sterile PBS: 5 mM
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-N22000
CAS No.: 14379-32-9
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Target:
Cat. No.: HY-P3818
CAS No.: 813416-46-5
Cat. No.: HY-P3818A
Cat. No.: HY-P990274
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Cat. No.: HY-P990303
Research Areas:
Cat. No.: HY-W127711
CAS No.: 14263-94-6
Cat. No.: HY-W150770
CAS No.: 1740-57-4
Synonyms: Isophthalic acid diamide
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Isophthalamide (Isophthalic acid diamide) is a widely used chemical scaffold for the design of high-performance fluorescent chemosensors.Isophthalamide, with its inherent hydrogen-bond-donating properties and tunable chelating cavity, enables highly selective recognition and detection of various analytes ranging from inorganic ions to complex organic molecules.Isophthalamide can be incorporated with various fluorophores to develop sensors displaying “turn-on” or “turn-off” signal responses.Isophthalamide-based sensors are thus capable of detecting diverse analytes including metal ions, anions, neutral molecules, pharmaceuticals, and explosives .
Cat. No.: HY-W612175
CAS No.: 1668-13-9
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H-Ala-pNA is an L-amino acid p-nitroaniline (pNA) derivative and a specific substrate for leukotriene A4 hydrolase. The D-enantiomer of H-Ala-pNA shows no activity toward leukotriene A4 hydrolase. H-Ala-pNA can be catalytically hydrolyzed by leukotriene A4 hydrolase, and the p-nitroaniline produced during the reaction is monitored spectrophotometrically at 405 nm to enable quantitative detection of enzyme activity. H-Ala-pNA is used to evaluate the potency of inhibitors targeting the amidase activity of leukotriene A4 hydrolase .
Cat. No.: HY-W800694
CAS No.: 2006335-63-1
Cat. No.: HY-W800838
CAS No.: 1466419-80-6
Cat. No.: HY-111391AR
CAS No.: 62758-13-8
Synonyms: Diazoresorcinol sodium, indicator (Standard)
Research Areas:
Resazurin (sodium), indicator (Standard) is the analytical standard of Resazurin (sodium), indicator (HY-111391A). This product is intended for research and analytical applications. Resazurin (Diazoresorcinol) sodium, indicator is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium, indicator is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium, indicator can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
Cat. No.: HY-137557
CAS No.: 1565797-16-1
Synonyms: APN1607; PM-PBB3
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Research Areas:
Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used for the detection of Alzheimer's disease (AD) and other tau proteinopathies. Its binding sites are located in the β-sheet of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein, as well as in the C-shaped cavity of SFs. In addition, APN-1607 binds to intraneuronal inclusions in Alzheimer's disease (AD), primary age-related tauopathy (PART) and posterior cortical atrophy (PCA). Florzolotau shows promise for PET imaging studies of neurological disorders, particularly tau proteinopathies .
Synonyms: 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole
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MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole) is a hydrophobic fluorescent probe that is used to detect conformational changes of the complement subcomponent C1r during its autoactivation process. MBD acts by selectively binding to exposed hydrophobic regions on the C1r macromolecule. The detection wavelength of MBD in the free unbound state is Ex/Em = 490/560 nm, whereas the maximum emission wavelength of MBD upon binding to C1r exhibits a blue shift of approximately 20 nm relative to 560 nm .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
