Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
940 Results for "
Rabbit
" in MedChemExpress (MCE) Product Catalog:
Products (940)
940 Results for "Rabbit" in MCE Product Catalog:
Target:
Research Areas:
Cat. No.: HY-W683499
CAS No.: 13197-76-7
Synonyms: LHSB
Target:
Research Areas:
Lauryl hydroxysultaine, 35% in H2O (LHSB) is a zwitterionic surfactant used in mid-to-high-end shampoos and body washes. Lauryl hydroxysultaine, 35% in H2O can also be applied in oil extraction, metal rust-preventive cleaners, paint removers, hard surface cleaners, and other fields .
Cat. No.: HY-15402
CAS No.: 210891-04-6
Synonyms: BMS 207940
Target:
Research Areas:
Edonentan (BMS 207940) is an orally active, highly selective endothelin A receptor (ETA receptor) antagonist with a Ki value of 0.01 nM against human targets. Edonentan blocks the pressor response induced by Big Endothelin-1 in conscious normotensive rats and the pressor response induced by ET-1 in conscious normotensive cynomolgus monkeys. Edonentan can be used in research related to cardiovascular diseases .
Cat. No.: HY-15402D
CAS No.: 264609-13-4
Synonyms: BMS 207940 hydrate
Target:
Research Areas:
Edonentan hydrate (BMS 207940 hydrate) is an orally active, highly selective endothelin A receptor (ETA receptor) antagonist with a Ki value of 0.01 nM against human targets. Edonentan hydrate blocks the pressor response induced by Big Endothelin-1 in conscious normotensive rats and the pressor response induced by ET-1 in conscious normotensive cynomolgus monkeys. Edonentan hydrate can be used in research related to cardiovascular diseases .
Cat. No.: HY-182301
CAS No.: 112227-15-3
Target:
Research Areas:
CP 71362 is a renin inhibitor, a highly potent substrate-analog transition state mimic with antihypertensive properties. CP 71362 exhibits significant inhibitory activity against plasma renin from rats, dogs, and humans (IC50 values are 3 nM, 0.0033 nM, and 20 nM, respectively). CP 71362 reduces the mean arterial pressure of anesthetized and conscious sodium-depleted animals in a dose-dependent manner, and has pharmacokinetic characteristics of rapid elimination and short duration of action. CP 71362 can be used in research related to hypertension and congestive heart failure .
Cat. No.: HY-P2142
CAS No.: 98353-69-6
Research Areas:
Troponin I (104-115) is a polypeptide derived from Troponin I. Troponin I is an inhibitor of Acto-S1-TM ATPase, with an IC50 of 2.25 μM against skeletal muscle Acto-S1-TM ATP enzyme . Troponin I is used in research on muscle contraction-relaxation and restrictive cardiomyopathy .
Cat. No.: HY-118968
CAS No.: 112946-90-4
Target:
Research Areas:
(-)-SA2572 is an orally active Ca 2+ inward channel inhibitor. (-)-SA2572 inhibits the slow Ca 2+ inward channel and the fast Na + inward channel. (-)-SA2572 inhibits depolarization-induced contraction of gastrointestinal smooth muscle and vascular smooth muscle, prolongs atrioventricular nodal conduction time, and inhibits His bundle-ventricular conduction time. (-)-SA2572 reduces systolic blood pressure in spontaneously hypertensive rats. (-)-SA2572 can be used in the research of hypertension .
Cat. No.: HY-183907
CAS No.: 89943-82-8
Target:
Research Areas:
Cicletanine is a voltage-dependent Ca 2+ channel inhibitor. Cicletanine inhibits α-adrenoceptor-mediated Ca 2+ release pathway, and shows vasodilatory effects on isolated vascular smooth muscle. Cicletanine directly stimulates lysosomal and cytoplasmic cholesteryl ester hydrolase activity. Cicletanine can be used for the research of hypertension .
Cat. No.: HY-N18431
CAS No.: 129744-24-7
Synonyms: ST-A TFA
Category:
Polysaccharides Iridoids Terpenoids Marine algae Marine natural products Sponge Saccharides
Target:
Cat. No.: HY-183405
CAS No.: 143984-56-9
Target:
Research Areas:
CD2019 is a selective retinoic acid receptor β (RARβ) agonist, with a Kd value of 26 nM for RARβ and an AC50 value of 3.8 nM for human RARβ. CD2019 regulates downstream biological effects via the PI3K signaling pathway. CD2019 suppresses squamous metaplasia, inhibits squamous differentiation markers, maintains pseudostratified epithelial structure, induces neurite and axon growth, and promotes functional recovery; it exhibits cytotoxicity at higher concentrations and reduces endogenous retinol levels. CD2019 can be used in studies related to squamous metaplasia, spinal cord injury and embryonic malformations .
Cat. No.: HY-W010973
CAS No.: 61-47-2
Category:
Natural Products Monophenols Metabolic Disease Phenols Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W010973R
CAS No.: 61-47-2
Cat. No.: HY-W010973S
CAS No.: 2687960-56-9
Research Areas:
5-Hydroxytryptamine-d4 creatinine sulfate monohydrate is the deuterated-labeled 5-Hydroxytryptamine creatinine sulfate monohydrate (HY-W010973). 5-Hydroxytryptamine creatinine sulfate monohydrate is a 5-HT receptor agonist and amine oxidase substrate that acts through multiple physiological responses, including induction of vasoconstriction, pressor effects, acceleration of platelet potassium exchange, and endothelium-dependent relaxation, and can serve as a radiolabeled substrate for organelle uptake assays. 5-Hydroxytryptamine creatinine sulfate monohydrate can be used in research on burns, tourniquet and botulinum shock .
Cat. No.: HY-P11698
CAS No.: 476667-31-9
Research Areas:
Cat. No.: HY-164295A
CAS No.: 133681-84-2
Research Areas:
U-78517 dihydrochloride, a Trolox (HY-101445) analog, is a potent antioxidant. U-78517 dihydrochloride inhibits DCVC (HY-19717)-induced lipid peroxidation, scavenges DPPH, oxygen- and nitrogen-based free radicals. U-78517 dihydrochloride attenuates hypoxic injury in iaolated cardiac myocytes. U-78517 dihydrochloride can be used for the research of hypoxic injury, cerebral ischemia, and cardiovascular disease .
Cat. No.: HY-180401
CAS No.: 139964-19-5
Target:
Research Areas:
DMP 811 is a potent, orally active and selective angiotensin II subtype receptor AT1 antagonist. DMP 811 exhibits selectivity for AT1 (IC50 = 6 nM) over AT2 (IC50 >10 μM). DMP 811 exhibits potent antihypertensive activity in rats and dogs. DMP 811 can be used for the research of hypertension .
Sulphadimethoxypyrimidine is an orally active, long-acting sulfonamide antibacterial agent, which is often administered in combination with Sulfamethazine (HY-B0035). Administration of Sulphadimethoxypyrimidine during pregnancy causes incisor malformations in rat offspring. Sulphadimethoxypyrimidine can be used in the research of bacterial infections .
Cat. No.: HY-135283
CAS No.: 212481-66-8
Synonyms: A-216546
Target:
Endothelin Receptor NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) Pyroptosis Interleukin Related
Research Areas:
ABT-546 (A-216546) is an orally active ETA receptor antagonist, with Ki values of 0.46 nM and 13000 nM for human ETA and ETB receptors, respectively, and exhibits >25000-fold selectivity over the ETB receptor. ABT-546 effectively inhibits ET-1 (HY-P0202)-induced phosphoinositide hydrolysis (IC50 = 0.59 nM) and arachidonic acid release (IC50 = 3.03 nM), and antagonizes ET-1-induced contraction in isolated vascular rings. ABT-546 crosses the placental barrier but shows extremely low fetal exposure, with a favorable safety profile. ABT-546 inhibits ET-1-induced pressor response and downregulates the NLRP3/ROS/GSDMD-mediated pyroptosis pathway. ABT-546 can be used for research on abdominal aortic aneurysm .
Cat. No.: HY-19309
CAS No.: 223756-43-2
Synonyms: A-216546 hydrochloride
Target:
Endothelin Receptor NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) Pyroptosis Interleukin Related
Research Areas:
ABT-546 (A-216546) hydrochloride is an orally active ETA receptor antagonist, with Ki values of 0.46 nM and 13000 nM for human ETA and ETB receptors, respectively, and exhibits >25000-fold selectivity over the ETB receptor. ABT-546 hydrochloride effectively inhibits ET-1 (HY-P0202)-induced phosphoinositide hydrolysis (IC50 = 0.59 nM) and arachidonic acid release (IC50 = 3.03 nM), and antagonizes ET-1-induced contraction in isolated vascular rings. ABT-546 hydrochloride crosses the placental barrier but shows extremely low fetal exposure, with a favorable safety profile. ABT-546 hydrochloride inhibits ET-1-induced pressor response and downregulates the NLRP3/ROS/GSDMD-mediated pyroptosis pathway. ABT-546 hydrochloride can be used for research on abdominal aortic aneurysm .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
