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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1460 Results for "
HINT1 polymerization
" in MedChemExpress (MCE) Product Catalog:
Products (1460)
1460 Results for "HINT1 polymerization" in MCE Product Catalog:
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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance [1].
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1 Cited Publications
Cat. No.: HY-176499
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PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates [1].
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1 Cited Publications
Cat. No.: HY-150761
Purity: 99.56%
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MY-875 is a competitive microtubulin polymerization inhibitor with an IC50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer activity [1].
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1 Cited Publications
Cat. No.: HY-126437K
CAS No.: 25988-63-0
Synonyms: PLL solution 0.01%, sterile-filtered, hydrobromide, MW 70000-150000, for cell culture
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1 Cited Publications
Synonyms: Auristatin PE; TZT-1027
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Soblidotin (Auristatin PE) is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization.
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1 Cited Publications
Cat. No.: HY-16114
CAS No.: 945771-74-4
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BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
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Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Disease Research Fields Berberidaceae Extract Cancer
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1 Cited Publications
Synonyms: Lys-Nε-MCC-DM1
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Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer [1] .
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Other Diseases Lignans Phenylpropanoids Plants Other Families Extract Disease Research Fields
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Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity [1] .
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1 Cited Publications
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Pironetin is an α/β unsaturated lactone isolated from Streptomyces species. Pironetin binds to α-tubulin and is a potent inhibitor of microtubule polymerization, and has cell cycle arrest and antitumor activity [1] .
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Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide [1] .
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1 Cited Publications
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Oryzalin is a dinitroaniline herbicide with antimitotic and antileishmanial activities. Oryzalin can bind to plant tubulin, inhibit the polymerization of microtubules in plant cells, and affect chromosome migration. Oryzalin can also be used to induce chromosome doubling [1] .
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1 Cited Publications
Cat. No.: HY-W440827
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery [1].
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1 Cited Publications
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MC-EVCit-PAB-MMAE (Linker-Payload 11) is a drug-linker conjugates for ADC. MC-EVCit-PAB-MMAE contains the ADCs linker (MC-EVCit-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162) [1].
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1 Cited Publications
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone
Category:
Tribulus terrester Linn. Alkaloids Piperidine Alkaloids Zygophyllaceae Extract Other Diseases Plants Disease Research Fields
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1 Cited Publications
Cat. No.: HY-N1131A
CAS No.: 33973-59-0
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
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Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) hydrochloride is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats [1] .
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1 Cited Publications
Cat. No.: HY-N1131B
CAS No.: 10581-38-1
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone monohydrate
Category:
Alkaloids Piperidine Alkaloids Other Diseases Plants Other Families Extract Disease Research Fields
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1 Cited Publications
Cat. No.: HY-B0015R
CAS No.: 33069-62-4
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1 Cited Publications
Synonyms: GBT-601; GBT-021601
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Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
