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Signaling Pathway

BNC105

HY-16114

(BNC-105)

BNC105

BNC105 Chemical Structure

BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.

Size Price Stock Quantity
10 mM * 1 mL in DMSO $385 In-stock
5 mg $350 In-stock
10 mg $500 In-stock
50 mg $1500 In-stock
100 mg $2100 In-stock
200 mg Get quote
500 mg Get quote
Size Price Stock Quantity
10 mM * 1 mL in DMSO €377 In-stock
5 mg €343 In-stock
10 mg €490 In-stock
50 mg €1470 In-stock
100 mg €2058 In-stock
200 mg Get quote
500 mg Get quote

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Inquiry Information
Product name: BNC105
Cat. No.: HY-16114

BNC105 Data Sheet

  • Network Version

    DataSheet

Related Compound Libraries

Biological Activity of BNC105

BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
IC50 value:
Target:
BNC105 exhibited excellent potency against a panel of different cancer cell lines with IC50 <1 nM for DU145, Calu-6, MDA-MB-231 etc. The selectivity observed for BNC105 against activated over quiescent HUVECs was also observed in human aortic arterial endothelial cells (HAAECs). BNC105 also exhibited good potency toward the cisplatin resistant cell line A2780cis.

Protocol (Extracted from published papers and Only for reference)

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Chemical Information

M.Wt 372.37 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C₂₀H₂₀O₇
CAS No 945771-74-4
Solvent & Solubility

10 mM in DMSO

Preparing Stock Solutions

1 mg 5 mg 10 mg
1 mM 2.6855 mL 13.4275 mL 26.8550 mL
5 mM 0.5371 mL 2.6855 mL 5.3710 mL
10 mM 0.2686 mL 1.3428 mL 2.6855 mL

References on BNC105

Inhibitor Kit

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