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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
139 Results for "
ICAM
" in MedChemExpress (MCE) Product Catalog:
Products (139)
139 Results for "ICAM" in MCE Product Catalog:
Cat. No.: HY-P74873
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; Intercellular Adhesion Molecule 1; Intercellular Adhesion Molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P703752
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; Intercellular Adhesion Molecule 1; Intercellular Adhesion Molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Species:
Canine
Source:
HEK293
Cat. No.: HY-P703780
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; Intercellular Adhesion Molecule 1; Intercellular Adhesion Molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P812002
Synonyms: ICAM4; Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group); CD242; LW; Intercellular Adhesion Molecule 4 (LW Blood Group); Landsteiner-Wiener Blood Group Glycoprotein; Intercellular Adhesion Molecule 4; CD242 Antigen; Intercellular Adhesion Molecule 4, Landsteiner-Wiener Blood Group; Landsteiner-Wiener Blood Group Antigen A; Landsteiner-Wiener Blood Group; LW Blood Group Protein; Bloodgroup LW Protein; LW Antigen A; ICAM-4
Cat. No.: HY-P812002A
Synonyms: ICAM4; Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group); CD242; LW; Intercellular Adhesion Molecule 4 (LW Blood Group); Landsteiner-Wiener Blood Group Glycoprotein; Intercellular Adhesion Molecule 4; CD242 Antigen; Intercellular Adhesion Molecule 4, Landsteiner-Wiener Blood Group; Landsteiner-Wiener Blood Group Antigen A; Landsteiner-Wiener Blood Group; LW Blood Group Protein; Bloodgroup LW Protein; LW Antigen A; ICAM-4
Cat. No.: HY-P99127
Target:
Research Areas:
Cat. No.: HY-135876
CAS No.: 29873-99-2
Synonyms: (-)-γ-Elemene
Cat. No.: HY-143243
CAS No.: 2684291-60-7
Research Areas:
Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway .
Cat. No.: HY-183516
CAS No.: 19220-35-0
Synonyms: OPG
Target:
Research Areas:
Osteoprotegerin (OPG) belongs to the tumor necrosis factor receptor (TNFR) superfamily . Osteoprotegerin blocks the RANKL-RANK interaction as well as the binding of TRAIL to its receptor. Osteoprotegerin activates NF-κB to induce the expression of ICAM-1, VCAM-1 and E-selectin, and activates the phosphorylation of ERK1/2. Osteoprotegerin regulates osteoclast activity, inhibits osteoclast maturation and formation, bone lysis and bone resorption, and increases bone mass. Osteoprotegerin regulates vascular endothelial cell function. Osteoprotegerin can be used in the research of cardio-cerebrovascular and bone-related diseases .
Cat. No.: HY-187620
CAS No.: 148550-96-3
Research Areas:
PD 144795 is an orally active inhibitor of E-selectin (E-selectin), ICAM-1, and VCAM-1, with IC50 values of 6.6 μM, 4.0-10 μM, and 4.0 μM for the human targets, respectively. PD 144795 has favorable pharmacokinetic properties, including good absorption and no endothelial cytotoxicity. PD 144795 inhibits TNF-α-induced adhesion of neutrophils and monocytes to endothelial cells, reduces neutrophil infiltration, exudate accumulation, and footpad swelling, and delays disease progression in rodent models. PD 144795 can be used for inflammation-related research .
Category:
Infection Alkaloids Microorganisms Other Alkaloids Marine natural products Disease Research Fields
Target:
Cat. No.: HY-15701R
CAS No.: 344897-95-6
Target:
Research Areas:
Leukadherin-1 (Standard) is the analytical standard of Leukadherin-1. This product is intended for research and analytical applications. Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling .
Cat. No.: HY-P72739
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; Dendritic Cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:
Human
Source:
HEK293
Cat. No.: HY-P76219
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; Dendritic Cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:
Human
Source:
HEK293
Cat. No.: HY-P76219A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; Dendritic Cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:
Human
Source:
HEK293
Cat. No.: HY-W051612
CAS No.: 16900-57-5
DL-Propargylglycine hydrochloride is an irreversible and selective CSE inhibitor that blocks the biosynthesis of endogenous hydrogen sulfide. DL-Propargylglycine hydrochloride induces ROS and TGF-β1 expression. DL-Propargylglycine hydrochloride downregulates carotid ACE2 and Ang-(1-7), and elevates Ang II. DL-Propargylglycine hydrochloride upregulates ICAM-1/LFA-1, exacerbating Aspirin (HY-14654)-induced gastric mucosal injury. DL-Propargylglycine hydrochloride is used in research on diabetes-induced liver injury, diabetic nephropathy, atherosclerosis, gastric mucosal injury, hemorrhagic shock, and Streptococcus agalactiae infection .
Cat. No.: HY-183448
CAS No.: 117666-86-1
Research Areas:
ETMTC is an orally active anti-inflammatory and antioxidant agent. ETMTC inhibits IKK-mediated phosphorylation and degradation of IkBα, blocks nuclear translocation and activation of NF-κB, and reduces the expression of ICAM-1, VCAM-1, E-selectin, Th2 cytokines and eosinophil chemokines. ETMTC abrogates neutrophil adhesion to endothelial monolayers and inhibits TNF-α-induced ROS production. ETMTC activates Nrf2, and enhances the activities of mitochondrial complex I and IV. ETMTC reduces lipid peroxidation levels, oxidative DNA damage, cytochrome c and caspase 9 activity, and decreases goblet cell metaplasia and subepithelial fibrosis. ETMTC can be used for the research of inflammatory diseases and asthma .
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
