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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
179 Results for "
Lenalidomide
" in MedChemExpress (MCE) Product Catalog:
Products (179)
179 Results for "Lenalidomide" in MCE Product Catalog:
Cat. No.: HY-W1115226
CAS No.: 3032320-74-1
Research Areas:
Desamino lenalidomide-piperidine-C-piperazine hydrochloride is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W1115227
CAS No.: 2963655-16-3
Research Areas:
Desamino lenalidomide-Pip-C-piperazine (trihydrochloride) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W584710
CAS No.: 2703770-71-0
Research Areas:
Desamino lenalidomide-C2-COOH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W777286
CAS No.: 1219332-91-8
Synonyms: CC-5013-13C5
rac-Lenalidomide- 13C5 (CC-5013- 13C5) is the 13C5-labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013) is an orally active immunomodulatory agent that binds CRBN as a molecular glue to alter substrate specificity, inducing ubiquitination and proteasome-dependent degradation of IKZF1, IKZF3 and CK1α. Lenalidomide induces apoptosis by degrading IKZF1/3, and activates p53 by degrading CK1α. Lenalidomide promotes IL-2 release and effector functions of CD8 + T/NK cells, while inhibiting TNF-α secretion and M1-type pyroptosis. Lenalidomide can be used in research related to hematological malignancies, acute liver failure and acute kidney injury .
Cat. No.: HY-46011
CAS No.: 2229714-16-1
Research Areas:
(3S)Lenalidomide-5-methylpiperazine benzenesulfonate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W1115239
CAS No.: 2851889-85-3
Research Areas:
Desamino lenalidomide-piperidine-F-C-piperazine is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W998277
CAS No.: 2207541-23-7
Research Areas:
Desamino lenalidomide-acetylene-C2-OH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-159618
Research Areas:
(3S)Lenalidomide-5-Pip-C-Pip-2C-Pip is an E3 Ligase Ligand-Linker Conjugate. (3S)Lenalidomide-5-Pip-C-Pip-2C-Pip can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608) .
Cat. No.: HY-W998278
CAS No.: 2138440-40-9
Research Areas:
Desamino lenalidomide-acetylene-C2-NH2 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W998279
CAS No.: 2229714-98-9
Research Areas:
Desamino lenalidomide-pent-4-yn-1-ol is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W998278A
CAS No.: 3065251-37-5
Research Areas:
Desamino lenalidomide-acetylene-C2-NH2 TFA is an E3 ligand-linker conjugate that incorporates a ligand based on CRBN and a linker, and can be used for the synthesis of PROTAC.
Cat. No.: HY-W1115229
CAS No.: 3032321-43-7
Research Areas:
Desamino lenalidomide-piperidine-O-7-azaspiro[3.5]nonane is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-180986
Research Areas:
Cis-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl is a synthetic E3 ligand-connector conjugate that can be used for the synthesis of Azo-PROTAC-4C-cis (HY-180985).
Cat. No.: HY-180984
Research Areas:
Trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl is a synthetic target E3 ligase ligand-conjugate linker, which can be used to synthesize Azo-PROTAC-4C-trans (HY-180983). Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader with anti-tumor activity .
Cat. No.: HY-W076696
CAS No.: 1061604-41-8
Target:
Research Areas:
Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.
Cat. No.: HY-W076696R
CAS No.: 1061604-41-8
Research Areas:
3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione (Standard) is the analytical standard of 3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione. This product is intended for research and analytical applications. Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.
Cat. No.: HY-133137A
CAS No.: 2821938-05-8
SJF620 hydrochloride is a PROTAC connected by ligands for Cereblon and Btk with a DC50 of 7.9 nM. SJF620 contains a Lenalidomide analog for recruiting CRBN .
Cat. No.: HY-W243404
CAS No.: 2304513-76-4
Target:
Research Areas:
3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research.
Cat. No.: HY-W243405
CAS No.: 2229976-08-1
Target:
Research Areas:
3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research.
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
