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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
195 Results for "
imaging agent
" in MedChemExpress (MCE) Product Catalog:
Products (195)
195 Results for "imaging agent" in MCE Product Catalog:
Cat. No.: HY-W009310R
CAS No.: 514-85-2
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Ferumoxytol is an FDA-approved ultrasmall superparamagnetic iron oxide preparation and iron replacement agent that exerts selective activity against leukemia cells with low ferroportin expression. Ferumoxytol increases intracellular iron levels, induces reactive oxygen species (ROS) production via the Fenton reaction, and triggers oxidative stress and cell death. Ferumoxytol reduces disease burden in mouse models and patient-derived leukemia models. As an MRI contrast agent, Ferumoxytol enables imaging of vascular lesions, tumors and lymph nodes. Ferumoxytol can be used in research related to acute myeloid leukemia and blast-phase chronic myeloid leukemia .
Synonyms: Fmoc-Asn(Ac3AcNH-beta-Glc)-OH
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Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) is an intermediate. Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH can be used in the synthesis of SiFA (silicon-fluoride acceptor)-octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .
Cat. No.: HY-W011696
CAS No.: 112-90-3
Synonyms: cis-1-Amino-9-octadecene, 80-90%
Cat. No.: HY-121364
CAS No.: 1416130-06-7
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Bodilisant is a histamine H3 receptor (hH3R) ligand and imaging/labeling agent, with a Ki value of 6.51 nM for hH3R. Bodilisant binds to hH3R to produce strong green fluorescence, localizes to the extracellular membrane without internalization, and generates clear, displaceable fluorescent labeling of hH3R in native human brain tissues. Bodilisant serves as a pharmacological tool to visualize the distribution of hH3R via fluorescence confocal laser scanning microscopy .
Cat. No.: HY-168929
CAS No.: 3113070-25-7
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SHP1 activator 1 (Compound 3n) is an activator for src homology-2 domain-containing protein tyrosine phosphatase 1(SHP1) with an EC50 of 17.66 μM. SHP1 activator 1 inhibits the proliferation of ABC-DLBCL cells, induces apoptosis by inhibiting STAT3 signaling pathway. SHP1 activator 1 emitts blue and green fluorescence signalis in MDA-MB-231 cell, and can be used as a cell imaging agent .
Cat. No.: HY-D1366
CAS No.: 2183440-68-6
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Sulfo-Cyanine5.5 carboxylic acid is a Fluorescent dye. Sulfo-Cyanine5.5 carboxylic acid emits red fluorescence, with a peak absorption wavelength of 673 nm. Sulfo-Cyanine5.5 carboxylic acid can be used to visualize aqueous sub-compartments and phase separation in synthetic multi-compartment microstructures. Sulfo-Cyanine5.5 carboxylic acid can serve as an intravenous contrast agent for in vivo cerebral perfusion imaging, mapping hemodynamics and perfusion regions .
Cat. No.: HY-D1366A
CAS No.: 2183440-69-7
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Sulfo-Cyanine5.5 carboxylic acid potassium is a Fluorescent dye. Sulfo-Cyanine5.5 carboxylic acid potassium emits red fluorescence, with a peak absorption wavelength of 673 nm. Sulfo-Cyanine5.5 carboxylic acid potassium can be used to visualize aqueous sub-compartments and phase separation in synthetic multi-compartment microstructures. Sulfo-Cyanine5.5 carboxylic acid potassium can serve as an intravenous contrast agent for in vivo cerebral perfusion imaging, mapping hemodynamics and perfusion regions .
Cat. No.: HY-P10913
CAS No.: 1186217-15-1
Cat. No.: HY-P10913A
Cat. No.: HY-145769
CAS No.: 2547100-02-5
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N2S2-CBMBC, an N2S2 bromo-benzyl ether derivative, acts as a ligand and use 99mTc-labelled complexes 99mTc-N2S2-CBMBC can be used as an imaging agent to be applied to the aspect of detecting PD-L1 expression, realize the real-time, comprehensive and convenient detection of the PD-L1 level of tumors, and overcome the defects of an immunohistochemical method .
Cat. No.: HY-187413A
Synonyms: DOPE-PEG2000-Mal-Cys-RRRRRRRR
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DOPE-PEG2000-R8 (DOPE-PEG2000-Mal-Cys-RRRRRRRR) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the R8 peptide (octaarginine, Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg), a cell-penetrating peptide. DOPE-PEG2000-R8 is used for enhanced intracellular delivery of drugs, nucleic acids, and imaging agents.
Cat. No.: HY-D0068
CAS No.: 139346-57-9
Synonyms: 7-Diethylaminocoumarin-3-carboxylic acid, SE
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DEAC, SE (7-Diethylaminocoumarin-3-carboxy acid, SE) is an amine-reactive fluorescent succinimidyl ester (NHS ester) dye that is excitable by a 405 nm laser and emits blue fluorescence. DEAC, SE covalently couples with APTES, incorporates into organosilica colloids through co-condensation with TPM or other silane coupling agents, and can also be used for post-synthetic infiltration labeling of porous titanium dioxide protrusions and covalent binding with surface hydroxyl groups. DEAC, SE is used for fluorescent labeling of colloidal particles and confocal microscopy imaging studies .
Cat. No.: HY-D3405
CAS No.: 173357-16-9
Cat. No.: HY-P11858
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Cat. No.: HY-W422109
CAS No.: 1345866-66-1
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4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging .
Cat. No.: HY-116450
CAS No.: 131615-52-6
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TISCH is a potent and selective iodinated ligand with high affinity and selectivity for CNS D1 dopamine receptors. TISCH showed a Kd value of 0.205 nM in rat striatal tissue, indicating its effectiveness in biological activity. TISCH is able to easily cross the blood-brain barrier and show distribution in specific areas with D1 receptor density. TISCH is considered to be useful as a pharmacological tool for characterizing D1 dopamine receptors. When labeled with I-123, TISCH has the potential to be used as an in vivo imaging agent for CNS D1 dopamine receptors .
Cat. No.: HY-128536
CAS No.: 2436544-28-2
Cat. No.: HY-181478
Hsp90-IN-45 is a Hsp90 inhibitor. Hsp90-IN-45 competitively binds to the ATP-binding site of purified Hsp90α with a Kd of 70 nM, blocks ATP hydrolysis, and disrupts Hsp90 client signaling. Hsp90-IN-45 inhibits ATPase activity of purified Hsp90α. Hsp90-IN-45 will be radiolabeled with 76/ 77Br for use as a radiotheragnostic agent for PET imaging and Meitner-Auger electron therapy. Hsp90-IN-45 can be used for the research of cancer .
Cat. No.: HY-182345
NOTA-MK0159 is a NOTA (HY-134418) and MK0159 (HY-150508) conjugate. NOTA-MK0159 inhibits human and mouse CD38 with IC50 values of 72.58 and 7.55 nM. NOTA-MK0159 coupled with radioactive elements acts as a imaging agent with specific uptake in CD38-positive multiple myeloma cells, enabling noninvasive whole-body assessment of CD38 expression in multiple myeloma xenografts. NOTA-MK0159 can be used for the research of multiple myeloma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
