TISCH
TISCH is a potent and selective iodinated ligand with high affinity and selectivity for CNS D1 dopamine receptors. TISCH showed a Kd value of 0.205 nM in rat striatal tissue, indicating its effectiveness in biological activity. TISCH is able to easily cross the blood-brain barrier and show distribution in specific areas with D1 receptor density. TISCH is considered to be useful as a pharmacological tool for characterizing D1 dopamine receptors. When labeled with I-123, TISCH has the potential to be used as an in vivo imaging agent for CNS D1 dopamine receptors.
For research use only. We do not sell to patients.
- CAS No.: 131615-52-6
- Formula: C17H17ClINO
- Molecular Weight:413.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 131615-52-6
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Molecular Weight 413.68
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Formula C17H17ClINO
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SMILES
OC1=C(C=C2CCN(C[C@@H](C2=C1)C3=CC=CC(I)=C3)C)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TISCH Related Classifications
HY-116450 Related Classifications
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