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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
258 Results for "
CaM
" in MedChemExpress (MCE) Product Catalog:
Products (258)
258 Results for "CaM" in MCE Product Catalog:
Cat. No.: HY-P75308
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK1; Doublecortin-Like And CaM Kinase-Like 1; Prev. DCaMKL1; Doublecortin-Like Kinase 1; DCDC3A; Doublecortin And CaM Kinase-Like 1; KIAA0369; CLICK1; DCLK; CL1; Doublecortin Domain-Containing Protein 3A; Doublecortin Like Kinase 1; Serine/Threonine-Pro
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181009
CAS No.: 3124773-51-6
HDAC-IN-98 is a HDAC1, HDAC2, HDAC3 inhibitor (one of the most selective class I HDAC inhibitors) with human IC50 values of 41.2 nM, 52.5 nM, and 74.3 nM respectively. HDAC-IN-98 induces H3K9 acetylation, p21 upregulation, G2/M arrest, cell apoptosis, has strong antiproliferative effects in colorectal cancer cells, low toxicity in healthy colon epithelium, modulates short-term in vitro effects via autophagy, and shows strong antitumor efficacy in vivo in the chorioallantoic membrane model (CAM) assay. HDAC-IN-98 can be used for the research of colorectal cancer .
Cat. No.: HY-180814
Target:
Research Areas:
SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer .
Cat. No.: HY-P75307
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK1; Doublecortin-Like And CaM Kinase-Like 1; Prev. DCaMKL1; Doublecortin-Like Kinase 1; DCDC3A; Doublecortin And CaM Kinase-Like 1; KIAA0369; CLICK1; DCLK; CL1; Doublecortin Domain-Containing Protein 3A; Doublecortin Like Kinase 1; Serine/Threonine-Pro
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702660
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK1; Doublecortin-Like And CaM Kinase-Like 1; Prev. DCaMKL1; Doublecortin-Like Kinase 1; DCDC3A; Doublecortin And CaM Kinase-Like 1; KIAA0369; CLICK1; DCLK; CL1; Doublecortin Domain-Containing Protein 3A; Doublecortin Like Kinase 1; Serine/Threonine-Protein Kinase DCLK1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702661
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; DCDC3; Prev. DCaMKL2; Doublecortin And CaM Kinase-Like 2; DCDC3B; MGC45428; DCK2; CLICK-II; Doublecortin-Like And CaM Kinase-Like 2; CLICK2; Serine/Threonine-Protein Kinase DCLK2; CL2; CaMK-Like CREB Regulatory Kinase 2; CLIK2; Doublecortin-Like Ki
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705803
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; DCDC3; Prev. DCaMKL2; Doublecortin And CaM Kinase-Like 2; DCDC3B; MGC45428; DCK2; CLICK-II; Doublecortin-Like And CaM Kinase-Like 2; CLICK2; Serine/Threonine-Protein Kinase DCLK2; CL2; CaMK-Like CREB Regulatory Kinase 2; CLIK2; Doublecortin-Like Ki
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706034
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DCLK1; Doublecortin-Like And CaM Kinase-Like 1; Prev. DCaMKL1; Doublecortin-Like Kinase 1; DCDC3A; Doublecortin And CaM Kinase-Like 1; KIAA0369; CLICK1; DCLK; CL1; Doublecortin Domain-Containing Protein 3A; Doublecortin Like Kinase 1; Serine/Threonine-Pro
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706031
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; DCDC3; Prev. DCaMKL2; Doublecortin And CaM Kinase-Like 2; DCDC3B; MGC45428; DCK2; CLICK-II; Doublecortin-Like And CaM Kinase-Like 2; CLICK2; Serine/Threonine-Protein Kinase DCLK2; CL2; CaMK-Like CREB Regulatory Kinase 2; CLIK2; Doublecortin-Like Ki
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-180524
CAS No.: 3014372-17-6
CAB7-3 is an orally active HBV capsid assembly modulator (CAM). CAB7-3 exhibits an exceptional antiviral efficacy reducing HBV DNA with an EC50 = 70 nM, CC50 = 32.3 μM in HepDES19 cells. CAB7-3 exhibits significant anti-HBV activity in HBV-integrated HepDES19 (EC50 = 70 nM), HepAD38 (EC50 = 1 nM) and HBV-infected HLCZ01 cells (EC50 = 2 nM), respectively. CAB7-3 effectively reduces Hepatic HBV core protein levels and suppresses viral replication in vivo. CAB7-3 demonstrates a favorable drug-like and safety profile. CAB7-3 can be used for Hepatitis B Virus (HBV) research .
Cat. No.: HY-184514
Target:
Research Areas:
TPA (bi (Tos))-γ-Glu (PEG23)-Glu-Val-Cit-PAB-PNU-159682 is a cleavable linker-payload conjugate, in which the payload is PNU-159682 (HY-16700) and the linker is TPA (bi (SH))-γ-Glu (PEG23)-Glu-Val-Cit-PAB (HY-184515). TPA (bi (Tos))-γ-Glu (PEG23)-Glu-Val-Cit-PAB-PNU-159682 is used to generate L1CAM-targeted antibody-drug conjugates (ADCs). TPA (bi (Tos))-γ-Glu (PEG23)-Glu-Val-Cit-PAB-PNU-159682 can be used in the research of metastatic triple-negative basal breast cancer and lung adenocarcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
