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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
258 Results for "
CaM
" in MedChemExpress (MCE) Product Catalog:
Products (258)
258 Results for "CaM" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-168022
CAS No.: 3056388-47-4
Target:
Research Areas:
CAM2602 is an orally active Aurora A-TPX2 protein−protein interaction inhibitor with a human Kd of 19 nM for Aurora A. CAM2602 increases the proportion of PH3 positive cells while reducing P-T288 Aurora A levels. CAM2602 arrests tumor xenograft growth in mice. CAM2602 can be used for the research of cancer, such as acute T cell leukemia .
1
1 Cited Publications
Cat. No.: HY-P7710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALM1; Epididymis Secretory Protein Li 72; Prev. CALML2; Calmodulin-3; DD132; CaMIII; PHKD1; CPVT4; CaMI; LQT14; PHKD; CALM3; Calmodulin 1 (Phosphorylase Kinase, Delta); CALM2; Phosphorylase Kinase Subunit Delta 1; CaM2; Phosphorylase Kinase Subunit Delta; CaM3; Prepro-Calmodulin 1; CaMB; Calmodulin-1; CaMC; Calmodulin 3 (Phosphorylase Kinase, Delta), Isoform CRA_b; CaM1; Calmodulin 1 (Phosphorylase Kinase, Delta), Isoform CRA_a; CALM; EF-Hand Calcium-Binding Domain-Containing Protein 11; CaM; CDNA FLJ61744, Highly Similar To Calmodulin; CaM; Phosphorylase Kinase, Delta Subunit; Calmodulin 1; Calmodulin-2
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P84930
Synonyms: Calcium/calmodulin dependent protein kinase II alpha antibody;
Calcium/calmodulin dependent protein kinase II beta antibody;
Calcium/calmodulin dependent protein kinase II delta antibody;
Calcium/calmodulin dependent protein kinase II gamma antibody;
Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody;
CaM kinase II alpha antibody;
CaM kinase II antibody;
CaM kinase II beta antibody;
CaM kinase II delta antibody;
CaM kinase II gamma antibody;
CaM kinase II subunit alpha antibody;
CaMK-II subunit alpha antibody;
CaMK2 antibody;
CaMk2a antibody;
CaMK2B antibody;
CaMK2D antibody;
CaMK2G antibody;
CaMKA antibody;
KCC2A_HUMAN antibody;
CaMKⅡ
1
1 Cited Publications
Target:
Research Areas:
Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca 2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca 2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP .
1
1 Cited Publications
Cat. No.: HY-P71002
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NRCaM; Uncharacterized Protein NRCaM; Neuronal Cell Adhesion Molecule; Ng-CaM-Related; NgCaM-Related Cell Adhesion Molecule; NRCaM Protein; Neuronal Surface Protein Bravo; NEDNMS; KIAA0343; HBravo; Bravo; Nr-CaM; Neuronal Cell Adhesion Molecule Short Isof
Species:
Human
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-P73749
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NCaM1; Alternative Protein NCaM1; Neural Cell Adhesion Molecule 1; CD56 Antigen; NCaM; N-CaM-1; CD56; NCaM-1; Antigen Recognized By Monoclonal Antibody 5.1H11; MSK39; Neural Cell Adhesion Molecule, NCaM
Species:
Rat
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77518
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDH1; CDHE; Prev. UVO; Epididymis Secretory Sperm Binding Protein; Uvomorulin; Cadherin 1, E-Cadherin (Epithelial); Epithelial Cadherin; Cell-CaM 120/80; E-Cadherin; CD324 Antigen; Cadherin-1; Arc-1; CD324; BCDS1; Cadherin 1, Type 1, E-Cadherin (Epithelia
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P75347
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CHL1; Cell Adhesion Molecule With Homology To L1CaM (Close Homolog Of L1); Cell Adhesion Molecule L1 Like; MGC132578; Close Homolog Of L1; FLJ44930; CALL; Cell Adhesion Molecule L1-Like; Neural Cell Adhesion Molecule L1-Like Protein; Neural Cell Adhesion
Species:
Human
Source:
HEK293
Cat. No.: HY-P99031
CAS No.: 1085337-57-0
Synonyms: CaM 3001
Target:
Research Areas:
Cat. No.: HY-P1805
CAS No.: 104041-80-7
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Cat. No.: HY-P1076A
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Research Areas:
Cat. No.: HY-P991646
Synonyms: heMab
Target:
Research Areas:
Cat. No.: HY-19805A
CAS No.: 1173022-21-3
Research Areas:
STO-609 acetate is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Cat. No.: HY-19230
CAS No.: 179185-73-0
Research Areas:
DY-9760e is a calmodulin (CaM) inhibitor. DY-9760e selectively inhibits the activity of various calmodulin-dependent enzymes by antagonizing the Ca²⁺/CaM complex, exhibiting the strongest inhibitory activity against nNOS, CaM kinase II, and calcineurin (Ki: 0.9, 1.4, and 2.0 μM, respectively). DY-9760e inhibits excessive nitric oxide production and protein tyrosine nitration, as well as the activation of calpain and caspase-3. DY-9760e reduces infarct size, improves cardiac function, and inhibits oxidative stress and cell death. DY-9760e can be used in research on the treatment of myocardial infarction, cerebral ischemia, and other diseases .
Cat. No.: HY-N10588
CAS No.: 443128-65-2
Synonyms: 10-epi-Nardoguaianone J
Category:
Valerianaceae Extract Terpenoids Sesquiterpenes Nardostachys jatamansi (D. Don) DC. Plants
Target:
Cat. No.: HY-123853
CAS No.: 2101206-81-7
Target:
Research Areas:
CAM4066 is a potent CK2α inhibitor, with an IC50 value of 300 nM. CAM4066 exhibits high selectivity, with IC50 values of 22.35, 43.55, and > 50 μM for HIPK3, DAPK3, and CLK2, respectively. CAM4066 shows no cell activity. CAM4066 can be used for the development of highly potent CK2 inhibitors .
Cat. No.: HY-129810
CAS No.: 130325-35-8
Synonyms: CaM 1028
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Research Areas:
PD 135158 (CAM 1028) is a selective CCKB receptor antagonist with an IC50 of 2.8 nM against mouse cortex CCKB. PD 135158 shows anxiolytic activity .
Cat. No.: HY-135698
CAS No.: 117339-76-1
Synonyms: M-CaM
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Research Areas:
Methocinnamox (M-CAM) a selective and long-acting μ-opioid receptor (MOR) antagonist with a Ki of 0.6 nM. Methocinnamox binds to the orthosteric site of the MOR in a pseudo-irreversible, non-covalent manner, resulting in prolonged receptor blockade that persists until new receptors are synthesized. Methocinnamox acts as a reversible antagonist at both the kappa-opioid receptor (KOR) (Ki = 4.9 nM) and delta-opioid receptor (DOR) (Ki = 2.2 nM), and it exhibits no intrinsic agonist activity at these receptors. Methocinnamox can be used to reverse and prevent opioid overdose and addiction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
