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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
110 Results for "
α-hydroxy acid
" in MedChemExpress (MCE) Product Catalog:
Products (110)
110 Results for "α-hydroxy acid" in MCE Product Catalog:
21
21 Publications Verification
Synonyms: 3α-hydroxy-5β-cholanic acid
Category:
Human Gut Microbiota Metabolites Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
11
11 Cited Publications
Synonyms: 17α-hydroxy-6α-methylprogesterone; U8840
Target:
Research Areas:
Medroxyprogesterone (17α-Hydroxy-6α-methylprogesterone) is a synthetic human variant of progesterone that is a progesterone receptor agonist with oral activity. Medroxyprogesterone can induce cell proliferation through the PI3K/Akt signaling pathway. Medroxyprogesterone has an inhibitory effect on atherosclerosis in mice. The progesterone agonist activity of Medroxyprogesterone is less effective than Medroxyprogesterone acetate (HY-B0469) .
8
8 Cited Publications
Cat. No.: HY-W018512
CAS No.: 4651-67-6
Synonyms: 3α-hydroxy-7-oxo-5β-cholanic acid
Target:
2
2 Cited Publications
Cat. No.: HY-B0172S
CAS No.: 83701-16-0
Synonyms: 3α-hydroxy-5β-cholanic acid-d4
1
Category:
Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite
Target:
1
1 Cited Publications
Synonyms: 1α-hydroxy vitamin D4
1alpha-Hydroxy VD4, a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
Synonyms: 2-hydroxyglutarate; 2-hydroxyglutaric acid; 2-hydroxypentanedioic acid
Target:
Research Areas:
6α-Hydroxy paclitaxel is one of the main metabolites of Paclitaxel (PTX) (HY-B0015), and it is generated by the liver cytochrome P450 enzyme CYP2C8. 6α-Hydroxy paclitaxel has bone marrow toxicity, but it can enhance the cytotoxicity of PTX against leukemia cells without causing cell toxicity. 6α-Hydroxy paclitaxel can be used in leukemia research .
Cat. No.: HY-N2489
CAS No.: 56786-63-1
Synonyms: Brassinosteroid BB 16; DI 31
Target:
Research Areas:
5α-Hydroxy-laxogenin (Brassinosteroid BB 16; DI 31) is a derivative of laxogenin, a spirostane-type steroid. 5α-Hydroxy-laxogenin serves as a plant-derived anabolic agent and is used as a dietary supplement .
Synonyms: 2-hydroxyglutarate disodium; 2-hydroxyglutaric acid disodium; 2-hydroxypentanedioic acid disodium
Target:
Cat. No.: HY-30216
CAS No.: 20312-37-2
Synonyms: D-α-hydroxyisocaproic acid
Target:
Research Areas:
3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism .
Synonyms: 2-hydroxyglutarate-13C5 disodium; 2-hydroxyglutaric acid-13C5 disodium; 2-hydroxypentanedioic acid-13C5 disodium
Cat. No.: HY-123349
CAS No.: 13027-33-3
Target:
Research Areas:
5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM .
Cat. No.: HY-30215
CAS No.: 13748-90-8
Synonyms: (S)-2-hydroxy-4-methylpentanoic acid
Synonyms: 2-hydroxyglutarate-d4 disodium; 2-hydroxyglutaric acid-d4 disodium; 2-hydroxypentanedioic acid-d4 disodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
