17 Results for "

γ-glutamyl transpeptidase

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "γ-glutamyl transpeptidase" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-114336
CAS No.: 11029-12-2
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W016586
CAS No.: 42228-92-2
Synonyms: AT-125; U-42126
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W016586A
CAS No.: 161922-40-3
Synonyms: AT-125 hydrochloride; U-42126 hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .
loading...
    loading...
Cat. No.: HY-113110
CAS No.: 19246-18-5
Purity:  99.96%
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
loading...
    loading...
Cat. No.: HY-N13356
CAS No.: 5652-48-2
Synonyms: gamma-glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
loading...
    loading...
Cat. No.: HY-W009749A
CAS No.: 535-34-2
Target:  

Drug Intermediate

Research Areas:  

Others

DL-Cystathionine is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine also is an intermediate in the biosynthesis of amino acid cysteine. DL-Cystathionine serves as a standard for quantifying tissue cystathionine .
loading...
    loading...
Cat. No.: HY-126710
CAS No.: 519170-13-9
Purity:  98.83%
Research Areas:  

Cancer

OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity .
loading...
    loading...
Cat. No.: HY-113456S
CAS No.: 1240398-17-7
Purity:  98.4%
Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
loading...
    loading...
Cat. No.: HY-146343
BMI-Glu is a selective γ-glutamyl transpeptidase (GGT) fluorescent probe with a Km of 69.63 µM. BMI-Glu has high sensitivity, good water solubility and biocompatibility .
loading...
    loading...
Cat. No.: HY-W016586AR
CAS No.: 161922-40-3
Synonyms: AT-125 hydrochloride (Standard); U-42126 hydrochloride (Standard)
Acivicin (hydrochloride) (Standard) is the analytical standard of Acivicin (hydrochloride). This product is intended for research and analytical applications. Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].
loading...
    loading...
Cat. No.: HY-W016586R
CAS No.: 42228-92-2
Synonyms: AT-125 (Standard); U-42126 (Standard)
Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .
loading...
    loading...
Cat. No.: HY-187024
CAS No.: 60133-17-7
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

D-GlupNA is a substrate of bovine kidney γ-glutamyl transpeptidase (γ-GluTP), which acts as a γ-glutamyl donor for acyl transfer and hydrolysis reactions. D-GlupNA can be hydrolyzed into glutamic acid and p-nitroaniline. D-GlupNA is applicable for metabolism-related research .
loading...
    loading...
Cat. No.: HY-169854
CAS No.: 3183-72-0
Research Areas:  

Others

N-γ-L-Glutamyl-4-aminobutyric acid (compound 8) is a substrate of γ-glutamyl transpeptidase (γ-GT). It can be used to study drug latency induced by γ-GT .
loading...
    loading...
Cat. No.: HY-D3170
C-HBrO-GGT is a dual-target fluorescent indicator with specificity for γ-glutamyl transpeptidase (GGT) and hypobromous acid (HBrO). C-HBrO-GGT acts as a substrate for GGT and HBrO, undergoing enzymatic or chemical modification to trigger channel-specific fluorescence, with sequential activation requiring initial GGT hydrolysis. C-HBrO-GGT enables simultaneous in vitro and in vivo fluorescence detection of GGT and HBrO. C-HBrO-GGT identifies mature atherosclerotic plaque positions and provides early warning of plaque formation before visual or classical immunofluorescent detection. C-HBrO-GGT can be used for the research of atherosclerosis (Ex/Em = 370 nm/500 nm) .
loading...
    loading...
Cat. No.: HY-P76361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGT5; Gamma-glutamyltranspeptidase 5; Prev. GGTLA1; GGT 5; Gamma-glutamyltransferase-Like Activity 1; Gamma-glutamyl transpeptidase-Related Protein; GGT-REL; Gamma-glutamyl Cleaving Enzyme; Gamma-glutamyl transpeptidase-Related Enzyme; GGT-Rel; Glutathion
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-D3188
CAS No.: 2730023-28-4
gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase (GGT) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT, and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma .
loading...
    loading...
Cat. No.: HY-D3187
CAS No.: 2484831-02-7
HMRef-αMan is a substrate-based green fluorescent probe (Ex/Em=465 nm/515 nm) targeting MAN2C1 (α-mannosidase). HMRef-αMan can be specifically cleaved by MAN2C1 to generate a highly fluorescent product, which thus gets activated to produce green fluorescence in malignant breast tissues, benign lesions and living cancer cells. The signal intensity of HMRef-αMan is directly correlated with MAN2C1 activity, and it can effectively detect tiny breast cancer lesions with a diameter of less than 1 mm. When used in combination with the red-emitting γ-glutamyl transpeptidase (GGT) probe gGlu-2OMe SiR600 (HY-D3188), HMRef-αMan enables precise optical differentiation of breast tissue types via a dual-color imaging strategy. HMRef-αMan has been widely used in the research of breast diseases such as breast cancer, fibroadenoma, phyllodes tumor and various types of papilloma .
loading...
    loading...
  • 1