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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
19S
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "19S" in MCE Product Catalog:
1
Cat. No.: HY-B1184A
CAS No.: 70989-04-7
Synonyms: (+)-Mephenytoin
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(S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .
Cat. No.: HY-B1184AR
CAS No.: 70989-04-7
Synonyms: (+)-Mephenytoin (Standard)
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(S)-Mephenytoin (Standard) is the analytical standard of (S)-Mephenytoin. This product is intended for research and analytical applications. (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .
Cat. No.: HY-159808
CAS No.: 875165-39-2
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TCL1 is a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit in the 19S regulatory particle (19S RP) of the proteasome with an IC50 value of approximately 26 μM. TCL1 interferes with the recognition and transport of ubiquitinated proteins by Rpn-13, inhibits the degradation of proteins by the proteasome, and thus affects the balance of intracellular protein metabolism. TCL1 is promising for research of hematological malignancies .
Cat. No.: HY-118332
CAS No.: 115461-39-7
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19(R)-HETE is a vasodilator in renal arteries, whereas 19(S)-HETE was relatively inactive .
Cat. No.: HY-N13334
CAS No.: 85372-70-9
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Cat. No.: HY-N13704
CAS No.: 874287-87-3
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Cat. No.: HY-N13530
CAS No.: 1616120-83-2
Category:
Triterpenes Tetracyclic Triterpenoids Terpenoids Cucurbitaceae Extract Plants Momordica charantia Linn.
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Cat. No.: HY-N13541
CAS No.: 1474062-47-9
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Cat. No.: HY-142972
CAS No.: 115461-40-0
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19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels .
Cat. No.: HY-157690
CAS No.: 2460392-58-7
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19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167) .
Cat. No.: HY-N1610
CAS No.: 16790-93-5
Synonyms: 20-Hydroxyconopharyngine
19(S)-Hydroxyconopharyngine (20-Hydroxyconopharyngine) is a natural product that can be isolated from Tabernaemontana bovina .
Cat. No.: HY-184563S
CAS No.: 3086790-98-6
Cat. No.: HY-CE00318
Synonyms: (S)-3-Hydroxy-19-methyleicosanoyl-coenzyme A
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(S)-3-Hydroxy-19-methyleicosanoyl-CoA ((S)-3-Hydroxy-19-methyleicosanoyl-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-P0184
CAS No.: 1002295-95-5
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Cat. No.: HY-P0184A
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Cat. No.: HY-157690A
CAS No.: 2242542-60-3
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19(R),20(S)-EDP (compound 19(S),20(R)-2a) is an oxylipin and a metabolite of docosahexaenoic acid (HY-B2167) .
Cat. No.: HY-181495
CAS No.: 2375455-53-9
Research Areas:
RAJQ14 is a BRD4 PROTAC-like CAP-TAC (Proteasome Cap Targeting Chimeras) degrader. RAJQ14 binds to 19S proteasome cap subunits RPN1, RPN10, RPN13, and USP14 to recruit target proteins to the proteasome for ubiquitination-independent, proteasome-dependent degradation. RAJQ14 can be used for the research of cancer (Pink: BRD4 Ligand (HY-181496); Blue: Proteasome Ligand (HY-128978); Black: Linker).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
