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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
3-o-me-m7g-5-ppp-5-g
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "3-o-me-m7g-5-ppp-5-g" in MCE Product Catalog:
Synonyms: m7g(5')ppp(5')(2'OMeA)pG ammonium
Synonyms: m7gpppA diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
Target:
Research Areas:
m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .
Cat. No.: HY-153108
Purity: 99.62%
Synonyms: ARCA cap solution (100 mM)
Cat. No.: HY-145969
CAS No.: 1093268-63-3
Synonyms: 3'-O-Me-m7g(5')ppp(5')G
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-145969A
Purity: 99.48%
Synonyms: 3’-O-Me-m7g(5')ppp(5')G triammonium
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) triammonium is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA triammonium binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA triammonium prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA triammonium has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-158772
Purity: 99.6%
Target:
Research Areas:
m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) is a trinucleotide cap analog with a Cap1 structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be co-transcriptionally incorporated into the 5' end of mRNA during T7 RNA polymerase-mediated in vitro transcription to form a natural Cap1 cap structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) enhances mRNA translation efficiency and reduces innate immune recognition, and it has been used in the preparation of self-amplifying mRNA rabies vaccines. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be applied to research related to in vitro mRNA transcription and mRNA vaccines .
Cat. No.: HY-145974
CAS No.: 62858-30-4
Synonyms: m7g(5')ppp(5')(2'OMeA)pG
Research Areas:
m7GpppAmpG (m7G(5')ppp(5')(2'OMeA)pG) is a trinucleotide 5′ cap analog. m7GpppAmpG binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG caps RNA with an efficiency of 90% and enhances mRNA stability and translation efficiency. m7GpppAmpG is used in mRNA therapeutic research .
Cat. No.: HY-145977A
Synonyms: m7g(5')ppp(5')(2'OMeG)pG ammonium
Cat. No.: HY-178602
CAS No.: 2222465-34-9
Target:
Research Areas:
CAP m7G(5')ppp(5')(2'OMeG) is a dinucleotide cap analog that can be used as a monomeric raw material for nucleic acid synthesis. CAP m7G(5')ppp(5')(2'OMeG) can be synthesized from 2'-O-Methyl-GDP and 7-Methylguanosine under the catalysis of guanylate transferase, and can be used as an intermediate to synthesize Cap2 structure trinucleotide cap analogs. Research on the synthesis of CAP m7G(5')ppp(5')(2'OMeG) for mRNA cap analogs is underway .
Cat. No.: HY-178673
CAS No.: 59985-44-3
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Research Areas:
M7G(5')ppp(5')(2'OMeA) is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-W1143084A
Target:
Research Areas:
m7G(5')ppp(5')(2'OMeG) ammonium is a cap analog that can be used for the synthesis of mRNA.
Cat. No.: HY-178673S
Cat. No.: HY-178671
CAS No.: 2734858-38-7
Target:
Research Areas:
CAP GAU m7G (5') ppp (5')(2'OMeA) pU is a trinucleotide cap analog with a Cap1 structure. CAP GAU m7G (5') ppp (5')(2'OMeA) pU can be co-transcriptionally incorporated into the 5' end of mRNA during T7 RNA polymerase-mediated in vitro transcription to form a natural Cap1 cap structure. CAP GAU m7G (5') ppp (5')(2'OMeA) pU enhances mRNA translation efficiency and reduces innate immune recognition, and it has been used in the preparation of self-amplifying mRNA rabies vaccines. CAP GAU m7G (5') ppp (5')(2'OMeA) pU can be applied to research related to in vitro mRNA transcription and mRNA vaccines .
Cat. No.: HY-185609
Target:
Research Areas:
m7G(2'F)(5')ppp(5')(2'OMeA)pG triammonium is a cap analog that can be used for the synthesis of mRNA.
Cat. No.: HY-178640
CAS No.: 3055894-68-0
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CAP m7G(LNA)(5')ppp(5')A(LNA)pG is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-185613
Target:
Research Areas:
m7G(UNA)(5')ppp(5')(2'OMeA)pG triammonium is a cap analog that can be used for the synthesis of mRNA.
Cat. No.: HY-185615
Target:
Research Areas:
m7G(HNA)(5')ppp(5')(2'OMeA)pG triammonium is a cap analog that can be used for the synthesis of mRNA.
Cat. No.: HY-178561
CAS No.: 2645354-92-1
Target:
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CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-185603
Target:
Research Areas:
m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG trisodium is a cap analog that can be used for the synthesis of mRNA.
Cat. No.: HY-145974AGL
CAS No.: 3080642-79-8
Synonyms: m7g(5')ppp(5')(2'OMeA)pG solution (100 mM) (GMP like)
Research Areas:
m7GpppAmpG ammonium solution (100 mM) (GMP-like) (m7G(5')ppp(5')(2'OMeA)pG solution (100 mM) (GMP-like)) is a GMP-like grade of m7GpppAmpG ammonium. m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5′ end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
